فعالیتهای تحقیقاتی دکتر مهرداد ایرانشاهی دانشيار گروه فارماكوگنوزي

امتیاز کاربران

ستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعالستاره غیر فعال
 

مشخصات فردي

نام: مهرداد

نام خانوادگي: ايرانشاهي

وضعيت تأهل: متأهل

مليت: ايراني

تاريخ تولد: 31/6/53

محل تولد: مشهد

زبانهاي مكالمه: فارسي و انگليسي

آدرس پستي: مشهد، بلوار وكيل‌آباد، دانشكده داروسازي، صندوق پستي: 1365-91775

شماره تلفن: 66-8823255-0511

شماره نمابر: 8823251-0511

پست الكترونيكي: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید يا  این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید

 

مدارك تحصيلي

  • ديپلم تجربي از دبيرستان سيد رضي – مشهد سال 1371
  • دكتراي داروسازي از دانشكده داروسازي تهران سال 1377
  • D. (دكتراي تخصصي) فارماكوگنوزي از دانشكده داروسازي تهران سال 1382

 

جوایز و افتخارات علمی

  • رتبه اول امتحان کشوری دوره تخصصي فارماكوگنوزي در سال 1377
  • رتبه دوم امتحان بورد تخصصي سال 1381
  • استاد برگزیده دانشگاه ، دومین همایش هم اندیشی اساتید دانشگاه علوم پزشکی کشور سال 1386
  • پژوهشگر برتر دانشگاه سال 1386
  • محقق جوان برتر از سوی معاونت تحقیقات و فن آوری وزارت بهداشت سال 1387
  • برگزیده سوم جشنواره رازی دوره 15 سال 1388
  • قرارگرفتن در فهرست یک درصد برتر دانشمندان جهان در گرایش داروشناسی و سم شناسی سال 1394 تاکنون

پاياننامههاي دكتراي داروسازي

1- بررسي فيتوشيميايي و استخراج كومارينهاي جاشيرساورزي (Prangos asperula)

2- بررسي اثر ليكوپن بر تكثير سلولهاي سرطاني پستان T47D و زير گروه مقاوم به تاموكسيفن آن TAMR-6

3- بررسي اثر ضد جنون گياه اسطوقدوس (Lavandula officinalis) در مدل حيواني

4- بررسي اثرات ضد درد دانه اسفند و جداسازي مواد مؤثره آن

5- بررسي اثرات ضد درد مشتقات وازيسينون در مقايسه با ايندومتاسين

6- جداسازي، خالص سازي و تعيين ساختمان فلاونوئيدهاي موجود در گياه تلخه بيان

7- شناسايي اجزاء اسانس ميوه Ferula badrakema به روش GC-MS و 13C-NMR و بررسي اثرات ضد ميكروبي اسانس

8- شناسايي اجزاء اسانس ميوه Ferula latisecta به روش GC-MS و 13C-NMR و بررسي اثرات ضد ميكروبي اسانس

9- بررسي اثرات هم افزايي فارنزيفرول A در E. coli مقاوم

10- بررسي اثرات هم افزايي گالبانيك اسيد در E. coli مقاوم

11- جداسازي، خالص سازي و تعيين ساختمان تركيبات موجود در اندامهاي هوايي كندل تركمنستاني

12- جداسازي، خالص سازي و تعيين ساختمان تركيبات موجود در ريشه كندل تركمنستاني

13- بررسي اثرات ضد تهوع فراكسيونهاي آويشن خراساني در جوجه

14- بررسي اثرات آنتي ژنوتوكسيسيتي گالبائيك اسيد به روش Commet assay

15- بررسي اثرات آنتي ژنوتوكسيسيتي تركيبات گوگرددار ريشه Ferula persica به روش Commet assay

16- بررسي اثرات ضد ليشمانيا اومبلي پرنين و اوراپتن بر روي پروماستيگوتهاي انگل لشمانيا

17- بررسي كامپيوتري اثرات امبلي پرنين روي آنزيم فارنزيل ترانسفراز و بررسي اثرات ضد سرطان آن روي سلولهاي سرطان كولون

18- بررسي درمنه‌هاي خراسان از لحاظ وجود تركيبات سزكوئي ترپن لاكتون به روشهاي TLC، IR و 1H-NMR

19- جداسازي و شناسايي تركيبات ميوه گياه Ferula badrakema

20- جداسازي و شناسايي تركيبات ريشه گياه Ferula diversivittata

21- بررسي اثرات ضد قارچ اسانس ميوه Ferula latisecta بر روي درماتوفيتهاي شايع پوستي

22- جداسازي و شناسايي تركيبات موجود در عصاره دي كلرومتاني Ferula ovina

23- بررسي روشهاي استخراج و خالص سازي ليكوپن از رب گوجه فرنگي

مقاوم S. aureus- بررسي اثرات هم افزايي گالبانيك اسيد در  24

25- جداسازي و شناسايي سزکوئی ترپن کومارین گلیکوزید های موجود در عصاره متانولیFerula badrakema

26- سنتز 7-پرنیلوکسی کومارینها

27- استخراج و خالص سازی ترکیبات گوگردی ریشه گیاه Ferula latisecta

28 - جداسازي و شناسايي تركيبات ريشه گياه Ferula flabelliloba

29- بررسی اثر آنتی ژنوتوکسیسیتی دایورسین به روش کامت

30- بررسی اثر مهاری 7-پرنیلوکسی کومارینها بر روی آنزیم استیل کولین استراز و بوتیریل کولین استراز

31- بررسی اثر هم افزایی کونفرول با آنتی بیوتیکها تتراسیکلین، متی سیلین و سیپروفلوکساسیلین علیه S. aureus مقاوم

32-  بررسی اثرات ضد فشار خون اوراپتن

33- افزایش غلظت پلاسمایی رزوراترول در تجویز همزمان با پیپرین

34- تعیین مقدار نئواریوسیترین و هسپریدین در آب لیموهای ایرانی

35- بررسی تأثیر تجویز کورکومین برHSP27 و بالانس اکسیدان-آنتی اکسیدان در انسان

36- استخراج،  خالص سازي و تعيين ساختمان آلکالوئيدهاي شاهتره و بررسي سميت سلولي آنها

37- استخراج،  خالص سازي و تعيين ساختمان آلکالوئيدهاي شقايق زيبا و بررسي سميت سلولي آنها

38- غربالگري ترکيبات سايتوتوکسيک اندامها مختلف تلخ بيان

39- غربالگري ترکيبات سايتوتوکسيک اسفنجهاي خليج فارس

40- غربالگري ترکيبات سايتوتوکسيک کلپوره واريته نافالوئيدس و فرولا اوپودا

41- استخراج،  خالص سازي و تعيين ساختمان کلپوره واريته نافالوئيدس

42- بررسی اثر سمیت سلولی گالبانیک اسید روکش داده شده روی نانو ذرات اکسید آهن

43- اثرات ضد التهاب خوراکی اوراپتن و اومبلی پرنین و اثرات آنها بر فاکتورهای التهاب مزمن

44- تهیه و ارزیابی فرم پلت از عصاره انار

45- تهیه و ارزیابی فرم پلت از اوراپتن

 

پایان نامه های تخصصی:

  • خالص سازی آلکالوئیدهای شبه داروی جنس فوماریاسه، بررسی سمیت سلولی آنها و رابطه ساختمان-اثر ترکیبات سایتوتوکسیک
  • خالص سازی سزکوئی ترپنهای کوزینیا، مشتق سازی آنها با آمین و بررسی سمیت سلولی آنها
  • خالص سازی سزکوئی ترپنهای سنتورا و بررسی سمیت سلولی آنها
  • تعیین ساختمان مطلق آلوپکورونها از گیاه تلخه بیان و بررسی قدرت اثر و مکانیسم سمیت سلولی آنها
  • خالص سازی ترکیبات سه گونه فرولا و یک گونه سوفورا و بررسی اثرات  مهاری آنها بر روی هیستون داستیلاز
  • بررسی فیتوشیمیایی و سمیت سلولی دو گونه جنس سالویا

کتب ترجمه یا تألیف:

  • روشهای سنجش بیولوژیک برای کشف داروهای جدید، ترجمه، انتشارات دانشگاه علوم پزشکی مشهد، سال 1389
  • روشهای جداسازی مواد مؤثره عصاره های طبیعی، ترجمه، انتشارات دانشگاه علوم پزشکی مشهد، سال 1389
  • دارودرمانی و تغذیه در اختلالات گفتارو زبان، تالیف، انتشارات دانشگاه علوم پزشکی مشهد، سال 1395

 

Publications:

 

1- Iranshahi M, Amin G, Amini M, Shafiee A (2003). Sulfur containing derivatives from Ferula persica  var.  latisecta. Phytochemistry, 63, 965-966.

2- Iranshahi M, Amin GR, Jalalizadeh H,    Shafiee A (2003).  New germacrane derivative from Ferula persica  Willd.  var.  latisecta Chamberlain. Pharmaceutical biology, 41, 6, 431-3.

3- Ziaee V, Jalalizadeh H, Iranshahi M, Shafiee A (2004). Improved synthesis of vasicinone. Iranian Journal of  Chemistry and Chemical Engineering, 23, 33-36.

4- Iranshahi M, Amin G, Shafiee A (2004). A new coumarin from  Ferula persica . Pharmaceutical  biology, 42, 6, 440-442.

5- Iranshahi M, Shahverdi AR, Mirjani R, Amin  G,  Abbas  Shafiee  (2004). Umbelliprenin from Ferula persica roots inhibits the red pigment production in Serratia marcescens . Zeitschrift für Naturforschung, 59 c, 506-508.

6-  Monsef HR, Ghobadi A, Iranshahi  M, Abdollahi M (2004). Antinociceptive effects of Peganum harmala L. alkaloid extract on mouse formalin test. Journal of pharmacy and pharmaceutical sciences, 7, 65-69.

7- Shahverdi AR, Mirjani R, Amin G, Shafiee A, Iranshahi M (2005). Bleaching of Serratia marcescens by some coumarins: A spectrophotometric study. Journal of Basic Microbiology, 45, 470-474.

8- Mirjani R, Shahverdi AR, Iranshahi M, Amin GR, Shafiee A (2005). Identification of Antifungal Compounds from Ferula persica var. persica. Pharmaceutical Biology, 43, 293-295.

9-  Shahverdi AR, Iranshahi M, Mirjani R, Jamalifar H, Amin GR, Shafiee A (2005). Bioassay-guided isolation and identification of an antibacterial compound from Ferula persica var.persica roots. DARU, 13, 17-19.

10- Fakhimi A, Iranshahi M, Emami SA, Amin-Ar-Ramimeh E, Zarrini G, Shahverdi AR (2006). Sophoraflavanone G from Sophora pachycarpa enhanced the antibacterial activity of gentamycin against Staphylococcus aureus. Zeitschrift für Naturforschung, 61c, 769-772.

11- Iranshahi M,  Amin G, Salehi Sourmaghi MH, Shafiee A, Hadjiakhoondi A (2006). Sulphur containing compounds in the essential oil of Ferula persica Willd. var. persica. Flavour and Fragrance Journal, 21, 2, 260-261.

12- Shahverdi AR, Saadat F, Khorramizadeh MR, Iranshahi M, Khoshayand MR (2006). Two matrix metalloproteinase from Ferula persica var. persica. Phytomedicine, 13, 712-717.

13- Mosaffa F, Behravan J, Karimi G, Iranshahi M (2006). Antigenotoxic effects of Satureja hortensis L. on rat lymphocytes exposed to oxidative stress. Archives of Pharmacal Research, 29, 159-164.

14- Iranshahi M, Arfa P, Ramezani M, Jaafari MR, Sadeghian H, Bassarello C, Piacente S, Pizza C (2007). Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. Phytochemistry, 68, 554-561.

15- Almasirad A, Amanzadeh Y, Taheri A, Iranshahi M (2007). Composition of a historical rose oil sample (Rosa damascena Mill. Rosaceae). Journal of Essential Oil Research, 19, 110-112.

16- Emami SA, Amin-Ar-Ramimeh E, Ahi A, Bolourian Kashy MR, Schneider B, Iranshahi M (2007). Prenylated flavonoids and flavonostilbenes from Sophora pachycarpa roots. Pharmaceutical Biology, 45, 453-457.

17- Iranshahi M, Shaki F, Mashlab M, Porzel A, Wessjohann LA (2007). Kopetdaghins A-E, sesquiterpene derivatives from the aerial parts and the roots of Dorema kopetdaghense. Journal of Natural Products, 70, 1240-1243.

18- Shahverdi AR, Fakhimi A, Zarrini G, Dehghan G, Iranshahi M (2007). Galbanic acid from Ferula szowitsiana enhanced the antibacterial activity of penicillin G and cephalexin against Staphylococcus aureus. Biological and Pharmaceutical Bulletin, 30, 1805-1807.

19- Behravan J, Mosaffa F, Karimi G, Iranshahi M (2007). In vitro protective effects of Satureja hortensis L. essential oil and ethanolic extract on lymphocytes DNA. Journal of Medicinal Plants, 6, 64-70.

20- Iranshahi, M, Emami SA, Mahmoud Soltani M (2007). Detection of sesquiterpene lactones in ten Artemisia species population of Khorasan provinces. Iranian Journal of Basic Medical Sciences, 10, 183-188.

21- Shahverdi AR, Moradkhani R, Mirjani R, Alimirzaee P, Monsef Esfehani HR, Iranshahi M, Gohari AR (2007). Enhancement effect of Berberis vulgaris var. integerrima seeds on the antibacterial activity of cephalosporins against Staphylococcus aureus and Escherichia coli. Iranian Journal of Pharmaceutical Sciences, 3, 181-186.

22- Barthomeuf C, Lim S, Iranshahi M, Chollet P (2008). Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis. Phytomedicine, 15, 103-111.

23- Iranshahi M, Mojarab M, Sadeghian H, Hanafi-Bojd MY, Schneider B (2008). Polar secondary metabolites of Ferula persica roots. Phytochemistry, 69, 473-478.

24- Iranshahi M, Kalategi F, Rezaee R, Shahverdi AR, Ito C, Furukawa H, Tokuda H, Itoigawa, M (2008). Cancer chemopreventive activity of terpenoid coumarins from Ferula species. Planta Medica, 74, 147-150.

25- Iranshahi M, Hassanzadeh-Khayyat MH, Fazly Bazzaz BS, Sabeti Z, Enayati F (2008). High content of polysulphides in the volatile oil of Ferula latisecta Rech. F. et Aell. fruits and antimicrobial activity of the oil. Journal of Essential Oil Research, 20, 183-185.

26- Iranshahi M, Hassanzadeh-Khayyat M, Sahebkar A, Famili A (2008). Chemical composition of the fruit oil of Ferula flabelliloba.  Journal of Essential Oil Bearing Plants, 11, 143-147.

27- Karimi G, Hassanzadeh M, Yazdanpanah H, Nazari F, Iranshahi M, Nili A (2008). Contamination of patulin in clear apple juice in Mashhad, Iran. Journal of Food Safety, 28, 413-421.

28- Iranshahi M, Amanzadeh Y (2008). Rapid isocratic HPLC analysis of caffeic acid derivatives from Echinacea purpurea cultivated in Iran. Chemistry of Natural Compounds, 44, 190-193.

29- Iranshahi M, Fata A, Emami B, Jalalzadeh Shahri BM, Fazly Bazzaz BS (2008). In vitro antifungal activity of polysulfides-rich essential oil of Ferula latisecta fruits against human pathogenic dermatophytes. Natural Product Communications, 3, 1543-6.

30- Iranshahi M, Hassanzadeh-Khayyat M (2008). Chemical composition of the volatile oil from Ferula ovina (Boiss.) Boiss. – Rech. fruits. Journal of Essential Oil Bearing Plants, 11, 350-355.

31- Iranshahi M, Hosseini ST, Shahverdi AR, Molazadeh K, Suleman Khan S, Ahmad VU (2008). Diversolides A-G, guaianolides from the roots of Ferula diversivittata. Phytochemistry, 69, 2753-2757.

32- Noroozi S, Mosaffa F, Soltani F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J (2009). Antigenotoxic effects of the disulfide compound persicasulfide A (PSA) on rat lymphocytes exposed to oxidative stress. Planta Medica, 75, 32-36.

33- Behnam Rasouli F, Matin MM, Iranshahi M, Bahrami AR, Neshati V, Mollazadeh S, Neshati Z (2009). Mogoltacin enhances vincristine cytotoxicity in human transitional cell carcinoma (TCC) cell line. Phytomedicine, 16, 181-187.

34- Iranshahi M, Rezaee R, Sahebkar A, Bassarello C, Piacente S, Pizza C (2009). Sesquiterpene coumarins from the fruits of Ferula badrakema. Pharmaceutiacal Biology, 47, 344-347.

35- Asili J, Sahebkar A, Fazly Bazzaz BS, Sharifi S, Iranshahi M (2009). Identification of essential oil components of Ferula badrakema fruits by GC-MS and 13C-NMR  methods and evaluation of its antimicrobial activity. Journal of Essential Oil Bearing Plants, 12, 7-15.

36- Iranshahi M, Chitsazian Yazdi M, Hassanzadeh-Khayyat M, Sahebkar A (2009). Sulfur containing compounds in the volatile oil of Ferula latisecta Rech. f. & Aell. leaves. Journal of Essential Oil Bearing Plants, 12, 64-68.

37- Soltani F, Mosaffa F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J (2009). Evaluation of antigenotoxicity effects of umbelliprenin on human peripheral lymphocytes exposed to oxidative stress. Cell Biology and Toxicology, 25, 291-296.

38- Moallem SA, Farahmand-Darzab A, Sahebkar A, Iranshahi M (2009). Antiemetic activity of different extracts from the aerial parts of Thymus vulgaris Klokov. Pharmacologyonline, 1, 1284-1292.

39- Askari M, Sahebkar A, Iranshahi M (2009). Synthesis and purification of 7-prenyloxycoumarins and herniarin as bioactive natural coumarins. Iranian Journal of Basic Medical Sciences, 12, 63-69.

40- Neshati V, Matin MM, Iranshahi M, Bahrani AR, Behravan J, Mollazadeh S, Behnam Rassouli F (2009). Cytotoxicity of vincristine on the 5637 cell line is enhanced by combination with conferone. Zeitschrift für Naturforschung, 64c, 317-322.

41- Iranshahi M, Sahebkar A, Takasaki M, Konoshima T, Tokuda H (2009). Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo. European Journal of Cancer Prevention, 18, 412-415.

42- Iranshahi M, Askari M, Sahebkar A, Hadjipavlou-Litina D (2009). Evaluation of antioxidant, anti-inflammatory and lypoxygenase inhibitory activities of the prenylated coumarin umbelliprenin. Daru, 17, 99-102.

43- Moghaddam KM, Iranshahi M, Chitsazian Yazdi M, Shahverdi AR (2009). The combination effect of curcumin with different antibiotics against Staphylococcus aureus. International Journal of Green Pharmacy, 3, 141-143.

44- Fazly Bazzaz BS, Rezaei Du A, Iranshahi M, Naderinasab M, Khajekaramodin M (2009). Evaluating the potentiating effect of galbanic acid from Ferula szowitsiana on three common antibiotics against resistant hospital isolates of Staphylococcus aureus. Iranian Journal of Pharmaceutical Research, 8, 217-221.

45- Iranshahi M, Noroozi S, Behravan J, Karimi G, Schneider B (2009). Persicasulphide A, a new sulphur-containinig derivative from Ferula persica. Natural Product Research, 17, 1584-1588.

46- Soltani F, Mosaffa F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J (2010). Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress. Phythoterapy Research, 24, 85-89.

47- Iranshahi M, Sahebkar A, Hosseini ST, Takasaki M, Konoshima T, Tokuda H (2010). Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo. Phytomedicine, 17, 269-273.

48- Iranshahi M, Kalateghi F, Sahebkar A, Sardashti A, Schneider B (2010). New sesquiterpene coumarins from the roots Ferula flabelliloba. Pharmaceutical Biology, 48, 217-220.

49- Bagheri SM, Sahebkar A, Gohari AR, Saeidnia S, Malmir M, Iranshahi M (2010). Evaluation of cytotoxicity and anticonvulsant activity of some Iranian medicinal Ferula species. Pharmaceutical Biology, 48, 242-246.

50- Iranshahi M, Ghiadi M, Sahebkar A, Rahimi A, Bassarello C, Piacente S and Pizza C (2009). Badrakemonin, a New Eremophilane-Type Sesquiterpene from the Roots of Ferula badrakema Kos.-Pol. Iranian Journal of Pharmaceutical Research, 8, 275-279.

51- Sahebkar A, Hassanzadeh-Khayyat M, Iranshahi M (2010). Quantitative analysis of the hydro-distilled essential oil of Ferula latisecta Rech. F. Aell. Roots from Iran. Journal of Essential Oil Bearing Plants, 13, 340-346.

52- Karimi G, Iranshahi M, Hosseinalizadeh F, Riahi B, Sahebkar A (2010). Screening of acetylcholinesterase inhibitory activity of terpenoid and coumarin derivatives from the genus Ferula. Pharmacologyonline, 1, 566-574.

53- Iranshahi M, Hosseini ST, Sahebkar A, Suleiman Khan S, Ahmad VU (2010). Diversivittatin, a new phenylpropanoid derivative from the roots of Ferula diversivittata. Chemistry of Natural Compounds, 46, 192-194.

54- Mollazadeh S, Matin MM, Iranshahi M, Bahrami AR, Neshati V, Behnam-Rasouli F (2010). The enhancement of vincristine cytotoxicity by combination with feselol. Journal of Asian Natural Products Research, 12, 569-575.

55- Fazly Bazzaz BS, Memariani Z, Khashiarmanesh Z, Iranshahi M, Naderinasab M (2010). Effect of galbanic acid, a sesquiterpene coumarin from Ferula szowitsiana, as an inhibitor of efflux mechanism in resistant clinical isolates of Staphylococcus aureus. Brazilian Journal of Microbiology, 41, 574-580.

56- Shahi M, Hanafi-Bojd AA, Iranshahi M, Vatandoost H, Hanafi-Bojd MY (2010). Larvicidal efficacy of latex and extract of Calotropis procera (Gentianales: Asclepiadaceae) against Culex quinquefasciatus and Anopheles stephensi (Diptera: Culicidae). Journal of Vector Borne Diseases, 47, 185-188.

57- Sahebkar A, Iranshahi M (2010). Cancer chemoprevention by 7-prenyloxycoumarins: a role for 5-lipoxygenase inhibition? Integrative Cancer Therapies, 9, 259-260.

58- Iranshahi M, Masullo M, Asili A, Hamedzadeh A, Jahanbin B, Festa M, Capasso A, Piacente S (2010). Sesquiterpene coumarins from Ferula gumosa. Journal of Natural Products, 73, 1958-1962.

59- Emami SA, Taghizadeh Rabe SZ, Iranshahi M, Ahi A, Mahmoudi M (2010). Sesquiterpene Lactone fraction from Artemisia khorassanica inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression through the inactivation of NF-κB. Immunopharmacology and Immunotoxicology, 32, 688-695.

60- Fazzly Bazzaz BS, Iranshahi M, Naderinasab M, Hajian S, Sabeti Z, Masumi E (2010). Evaluation of Effects of galbanic acid from Ferula szowitsiana and conferol from F.badrakema, as modulators of multi-drug resistance in clinical isolates of Escherichia coli and Staphylococcus aureus. Research in Pharmaceutical Sciences, 5, 21-28.

61- Khorramizadeh MR, Esmail-Nazari Z, Zarei-Ghaane Z, Shakibaie M, Mollazadeh-Moghaddam K, Iranshahi, M, Shahverdi, AR (2010). Umbelliprenin-coated Fe3O4 magnetite nanoparticles: Antiproliferation evaluation on human Fibrosarcoma cell line (HT-1080), Materials Science and Engineering, 30, 1038-1042.

62- Sahebkar A, Iranshahi M (2010). Biological activities of essential oils from the genus Ferula (Apiaceae). Asian Biomedicine, 4, 835-847.

63- Iranshahi M, Famili A, Bassarello C, Piacente S, Pizza C (2010). Purification and structure elucidation of compounds from the roots of Ferula ovina Bioss. Journal of Medicinal Plants, 9, 72-80.

64- Kohno S, Murata T, Sugiura A, Ito C, Iranshahi M, Hikita K, Kaneda N (2011). Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells. Journal of Natural Medicines, 65, 353-359.

65- Nazari ZE, Iranshahi M (2011). Biologically active sesquiterpene coumarins from Ferula species. Phytotherapy Research, 25, 315-323.

66- Rasouli FB, Matin MM, Iranshahi M, Bahrami AR, Behravan J, Mollazadeh S, Neshati V, Kalalinia F (2011). Investigating the enhancement of cisplatin cytotoxicity on 5637 cells by combination with mogoltacin. Toxicology in vitro, 25, 469-474.

67- Iranshahy M, Iranshahi M (2011). Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assafoetida oleo-gum-resin) – A review. Journal of Ethnopharmacology, 134, 1-10.

68- Hanafi-Bojd MY, Iranshahi M, Mosaffa F, Omidvar Tehrani S, Kalalinia F, Behravan J (2011). Farnesiferol A from Ferula persica and galbanic acid from Ferula szowitsiana inhibit P-glycoprotein-mediated rhodamine efflux in breast cancer cell lines. Planta Medica, 77,  1590-1593.

69- Rassouli FB, Matin MM, Iranshahi M, Bahrami AR (2011). Investigating the cytotoxic and apoptosis inducing effects of monoterpenoid stylosin in vitro. Fitoterapia, 82, 742-749.

70- Saeidi I, Hadjmohammadi MR, Peyrovi M, Iranshahi M, Barfi B, Babaei AB,  Mohammaddoost A (2011). HPLC determination of hesperidin, diosmin and eriocitrin in Iranian lime juice using polyamide as an adsorbent for solid phase extraction. Journal of Pharmaceutical and Biomedical analysis, 56, 419-422.

71- Bolandghamat S, Moghimi A, Iranshahi M (2011). Effects of ethanolic extract of pine needles (Pinus eldarica Medw.) on reserpine-induced depression-like behavior in male rats. Pharmacognosy Magazine, 7, 248-253.

72- Sahebkar A, Iranshahi M (2011). Volatile constituents of the genus Ferula (Apiaceae): A review. Journal of Essential Oil Bearing Plants, 14, 504-531.

73- Gholamnezhad Z, Byrami G, Boskabady MH, Iranshahi M (2011). Possible mechanism(s) of the relaxant effect of asafoetida (Ferula assa-foetida) oleo-gum-resin extract on guinea-pig tracheal smooth muscle. Avicenna Journal of Phytomedicine, 2, 10-16.

74- Mollazadeh S, Matin M M, Bahrami AR, Iranshahi M, Behnam-Rassouli M, B. Rassouli  F, Neshati V (2011). Feselol Enhances the Cytotoxicity and DNA Damage Induced by Cisplatin in 5637 Cells. Zeitschrift für Naturforschung, 66, 555-561.

75- Iranshahi M, Vu H, Pham N, Zencak D, Forster P, Quinn RJ (2012). Cytotoxic evaluation of alkaloids and isoflavonoids from the Australian tree Erythrina vespertilio. Planta Medica, 7, 730 -736.

76- Akhlaghi F, Rajaei Z, Hadjzadeh M, Iranshahi M, Alizadeh M (2012). Antihyperglycemic effect of Asafoetida (Ferula assa-foetida oleo-gum-resin) in stroptozotocin-induced diabetic rats. World Applied Sciences journal, 17, 157-162.

77- Suleman Khan S, Khan A, Marasini B P, Saba N, Ahmad VU, Iranshahi M,Hosseini ST, Choudhary MI (2012). α-Chymotrypsin and Urease Inhibitory Activity of Diversolides C, D and E from the Roots of Ferula Diversivittata. Journal of the Chemical Society of Pakistan, 34, 699-701.

78- Ziai SA, Gholami O, Iranshahi M, Zamani AH, Jeddi-Tehrani M (2012). Umbelliprenin Induces Apoptosis in CLL Cell Lines. Iranian Journal of Pharmaceutical Research, 11, 653-659.

79- Iranshahi M, Amanollahi F, Schneider B (2012). New sesquiterpene coumarin from the roots of Ferula latisecta. Avicenna Journal of Phytomedicine, 2, 133-138.

80- Iranshahi M (2012). A review of volatile sulfur-containing compounds from terrestrial plants: biosynthesis, distribution and analytical methods. Journal of Essential Oil Research, 24, 393-434.

81- Neshati V, Matin MM, Bahrami AR, Iranshahi M, Rassouli FB, Saeinasab M (2012). Increasing the cisplatin cytotoxicity and cisplatin-induced DNA damage by conferone in 5637. Natural Product Research, 26, 1724-1727.

82- Iranshahi M, Jabbari A, Orafaie A, Mehri R, Zeraatkar S, Ahmadi T, Alimardani M, Sadeghian H (2012). Synthesis and SAR studies of mono O-prenylated coumarins as potent 15-lipoxygenase inhibitors. European Journal of Medicinal Chemistry, 57, 134-142.

83- Sajed H, Sahebkar A, Iranshahi M (2013). Zataria multiflora Bioss. (Shirazi thyme)-An ancient condiment with modern pharmaceutical uses. Journal of Ethnopharmacology, 145, 686-698.

84- Tourchi Rudsari M, Bahrami AR, Dehghani H, Iranshahi M, Matin MM, Mahmoudi M (2012). Bracken-fern extracts induce cell cycle arrest and apoptosis in certain cancer cell line. Asian Pacific Journal of Cancer Prevention, 13, 6047-6053.

85- Imenshahidi M, Eghbal M, Sahebkar A, Iranshahi M (2013). Hypotensive activity of auraptene, a monoterpene coumarin from Citrus spp. Pharmaceutical Biology, 51, 545-549.

86- Zarei H, Rezaee R, Behravan E, Soltani F, Mosaffa F, Iranshahi M, Behravan J (2013). Diversin, from Ferula diversivittata protects human lymphocytes against oxidative stress induced by H2O2. Natural Product Research, 27, 1016-1019.

87- Mohammadi A, Sahebkar A, Iranshahi M, Amini M, Khojasteh R, Ghayour-Mobarhan M, Ferns GA (2013). Effects of supplementation with curcuminoids on dyslipidemia in obese patients: A randomized crossover trial. Phytotherapy Research, 27, 374-379.

88- Iranshahy M, Mohammadpoor AH, Hassanzadeh-Khayyat M, Iranshahi M (2013). Method validation of one-month stability study of trans-resveratrol in human plasma. Jundishapur Journal of Natural Pharmaceutical Products, 8, 65-69.

89- Mahmoudi Z, Soleimani M, Saidi A, Iranshahi M, Azizsoltani A (2013). Effect of Ferula gummosa ethanolic extract on osteogenesis in human mesenchymal stem cells. Journal of Medicinal Plants, 12, 50-59.

90- Gholami O, Jeddi-Tehrani M, Iranshahi M, Zarnani AH, Ziai SA (2013). Umbelliprenin from Ferula szowitsiana activates both intrinsic and extrinsic pathways of apoptosis in Jurkat T-CLL cell line. Iranian Journal of Pharmaceutical Research, 12, 371-376.

91- Valiahdi SM, Iranshahi M, Sahebkar A (2013). Cytotoxic activities of phytochemicals from Ferula species. Daru Journal of Pharmaceutical Sciences, 21, 39-46.

92- Shiezadeh F, Mousavi SH, Amiri MS, Iranshahi M, Tayarani-Najaran Z, Karimi G (2013). Cytotoxic and apoptotic potential of Rheum turkestanicum Janisch root extract on human cancer and normal cells. Iranian Journal of Pharmaceutical Research, 12, 811-819.

93- Iranshahi M, Esfahanizadeh T, Jalili-Jamshidian E, Hanafi-Bojd MH, Malaekeh-Nikouei B (2013). Improvement aqueous solubility of the prenylated coumarins using cyclodextrin complexation. International Journal of Pharmaceutical Sciences, 5, 40-42.

94- Sahebkar A, Mohammadi A, Atabaki A, Rahiman S, Tavallaie S, Iranshahi M, Akhlaghi S, Ferns GAA, Ghayour-Mobarhan M (2013). Curcuminoids modulate pro-oxidant-antioxidant balance but not the immune response to heat shock protein 27 and oxidized LDL in obese individuals. Phytotherapy Research, 27, 1883-1888.

95- Kasaian J, Iranshahy M, Iranshahi M (2014). Synthesis, biosynthesis and biological activities of galbanic acid - a review. Pharmaceutical Biology, 52, 524-531.

96- Kasaian J, Iranshahy M, Masullo M, Piacente S, Ebrahimi F, Iranshahi M (2014). Sesquiterpene lactones from Ferula oopoda and their cytotoxic properties. Journal of Asian Natural Products Research, 16, 248-253.

97- Firouzi Z, Lari P, Rashedinia M, Ramezani M, Iranshahi M, Abnous K (2014). Proteomics screening of molecular targets of curcumin in mouse brain. Life Sciences, 98, 12-17.

98- Rezaee R, Behravan E, Behravan J, Soltani F, Naderi N, Emami B, Iranshahi M (2014). Antigenotoxic activities of the natural dietary coumarins umbelliferone, herniarin and 7-isopentenyloxy coumarin on human lymphocytes exposed to oxidative stress. Drug and Chemical Toxicology, 37, 144-148.

99- Haghighitalab A, Matin MM, Bahrami AR, Iranshahi M, Haghighi F, Porsa H (2014). Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro. Drug and Chemical Toxicology, 37, 156-162.

100- Iranshahy M, Quinn RJ, Iranshahi M (2014). Biologically active isoquinoline alkaloids with drug-like properties from the genus Corydalis. RSC Advances, 4, 15900-15913.

101- Haghighi F, Matin MM, Bahrami AR, Iranshahi M, Rassouli FB, Haghighitalab A (2014). The cytotoxic activities of 7-isopentenyloxycoumarin on 5637 cells via induction of apoptosis and cell cyclearrest in G2/M stage. Daru Journal of Pharmaceutical Sciences, 22, 1-10.

102- Iranshahi M, Barthomeuf C, Bayet-Robert M, Chollet P, Davoodi D, Piacente S, Rezaee R, Sahebkar A (2014). Drimane-type sesquiterpene coumarins from Ferula gummosa fruits enhance doxorubicin uptake in doxorubicin-resistant human breast cancer cell line. Journal of Traditional and Complementary Medicine, 4, 118-125.

103- Matin MM, Nakhaeizadeh H, Bahrami AR, Iranshahi M, Arghiani N, Behnam-Rassouli F (2014). Ferutinin, an apoptosis inducing terpenoid from Ferula ovina. Asian Pacific Journal of Cancer Prevention, 15, 2123-2128.

104- Haghighitalab A, Matin MM, Bahrami AR, Iranshahi M, Saeinasab M, Haghighi F (2014). In vitro investigation of anticancer, cell-cycle-inhibitory, and apoptosis-inducing effects of diversin, a natural prenylated coumarin on bladder carcinoma cells. Zeitschrift für Naturforschung, 69, 99-109.

105- Safdari H, Neshati A, Sadeghian A, Ebrahimi M, Iranshahi M, Sadeghian M (2014). Potent and selective inhibitors of class A β-lactamase: 7-prenyloxy coumarins. Journal of Antibiotics, 67, 373-377.

106- Ramezani A, Iranshahi M, Hanafi-Bojd MY, Malaekeh-Nikouei B (2014).  Preparation, characterization and cytotoxic effects of nanoliposomes containing umbelliprenin. International Journal of Pharmaceutical Research, 6, 79-84.

107- Arghiani N, Matin MM, Bahrami AR, Iranshahi M, Sazgarnia A, Rassouli FB (2014). Investigating anticancer properties of the sesquiterpene ferutinin on colon carcinoma cells, in vitro and in vivo. Life Sciences, 109, 87-94.

108- Roohbakhsh A, Parhiz H, Soltani F, Rezaee R, Iranshahi M (2014). Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin – A mini-review. Life Sciences, 113, 1-6.

109- Shirani K, Behravan J, Mosaffa F, Iranshahi M, Mehmankhah B, Razavi-Azarkhiavi K, Karimi G (2014). Evaluating the effects of galbanic acid on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes. Avicenna Journal of Phytomedicine, 4, 337-342.

110- Gholami O, Jeddi-Tehrani M, Iranshahi M, Zarnani AH, Ziai SA (2014). Mcl-1 is upregulated by prenylated coumarin, umbelliprenin in Jurkat cells. Iranian Journal of Pharmaceutical Research, 13, 1385-1390.

111- Shakeri A, Iranshahy M, Iranshahi M (2014). Biological properties and molecular targets of umbelliprenin – a mini-review. Journal of Asian Natural Products Research, 16, 884-889.

112- Iranshahy M, Javidi-Shirazi H, Pham NB, Quinn RJ, Sadeghian H, Iranshahi M (2014). Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii. Journal of Asian Natural Products Research, 16, 1148-1152.

113- Chitsazian-Yazdi M, Agnolet S, Lorenz S, Schneider B, Es’Haghi Z, Kasaian J, Khameneh B, Iranshahi M (2015). Foetithiophenes C-F, thiophene derivatives from the roots of Ferula foetida. Pharmaceutical Biology, 53, 710-714.

114- Zamani Taghizadeh Rabe S, Emami SA, Iranshahi M, Rastin M, Tabasi N, Mahmoudi M (2015). Anti-cancer Properties of a sesquiterpene lactone-bearing fraction from Artemisia khorassanica. Asian Pacific Journal of Cancer Prevention, 16, 863-868.

115-  Hashemzaei M, Sadeghi Bonjar MA, Tabrizian K, Iranshahi M, Iranshahy M, Rezaee R (2015). Evaluation of the analgesic effect of Umbelliprenin and Umbelliprenin-morphine co-administration on the acute, chronic and neuropathic pain. Indian Journal of Pharmaceutical Education and Research, 49, 121-125.

116- Akaberi M, Mehri S, Iranshahi M (2015). Multiple pro-apoptotic targets of abietane diterpenoids from Salvia species. Fitoterapia, 100, 118-132.

117- Rezaie M, Farhoosh R, Iranshahi M, Sharif A, Golmohamadzadeh S (2015). Ultrasonic-assisted extraction of antioxidative compounds from Bene (Pistacia atlantica subsp. mutica) hull using various solvents of different physicochemical properties. Food Chemistry, 173, 577-583.

118- Roohbakhsh A, Parhiz F, Soltani F, Rezaee R, Iranshahi M (2015). Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases. Life Sciences, 124, 64-74.

119- Razavi BM, Arasteh E, Imenshahidi M, Iranshahi M (2015). Antihypertensive effect of auraptene, a monoterpene coumarin from the genus Citrus, upon chronic administration. Iranian Journal of Basic Medical Sciences, 18, 153-158.

120- Parhiz H, Roohbakhsh A, Soltani F, Rezaee R, Iranshahi M (2015). Antioxidant and anti-inflammatory properties of the citrus flavonoids hesperidin and hesperetin: An updated review of their molecular mechanisms and experimental models. Phytotherapy Research, 29, 323-331.

121- Zamani Taghizadeh Rabe S, Iranshahi M, Rastin M, Zamani Taghizadeh Rabe S, Mahmoudi M (2015). Anti-inflammatory effect of new kopetdaghins A, C and E from Dorema kopetdaghense. Food and Agricultural Immunology, 26, 430-439.

122- Rezaie M, Farhoosh, R, Sharif A, Asili J, Iranshahi M (2015). Chemical composition, antioxidant and antibacterial properties of Bene (Pistacia atlantica subsp. mutica) hull essential oil. Journal of Food Science and Technology, 52, 6784-6790.

123- Esmaily H, Sahebkar A, Iranshahi M, Ganjali S, Mohammadi A, Ferns G, Ghayour-Mobarhan M (2015). An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial. Chinese Journal of Integrative Medicine, 21, 332-338.

124- Oh BS, Shin EA, Jung JH, Jung DB, Kim B, Shim BS, Chitsazian-Yazdi M, Iranshahi M, Kim SH (2015). Apoptotic effect of galbanic acid via activation of caspases and inhibition of Mcl-1 in H460 non-small lung carcinoma cells. Phytotherapy Research, 29, 844-849.

125- Kasaian J, Mosaffa F, Behravan J, Masullo M, Piacente S, Ghandadi M, Iranshahi M (2015). Reversal of P-glycoprotein-mediated multidrug resistance

in MCF-7/Adr cancer cells by sesquiterpene coumarins. Fitoterapia, 103, 149-154.

126- Zamani Taghizadeh Rabe S, Iranshahi M, Rastin M, Tabasi N, Mahmoudi M (2015). In vitro immunomodulatory properties of a sesquiterpene lactone-bearing fraction from Artemisia khorassanica. Journal of Immunotoxicology, 12, 223-230.

127- Amirchaghmaghi M, Delavarian Z, Iranshahi M, Taghi Shakeri M, Mozaffari PM, Mohammadpour A, Farazi F, Iranshahy M (2015). A randomized placebo-controlled double blind clinical trial of quercetin for treatment of oral lichen planus. Journal of Dental Research, Dental Clinics, Dental Prospects, 9, 1-6.

128- Khamaneh B, Iranshahy M, Ghandadi M, D Ghoochi Atashbeyk, Fazly Bazzaz BS, Iranshahi M (2015). Investigation of the antibacterial activity and efflux pump inhibitory effect of co-loaded piperine and gentamicin nanoliposomes in methicillin-resistant Staphylococcus aureus. Drug Development and Industrial Pharmacy, 41, 989-994.

129- Khameneh B, Jaafari MR, Hassanzadeh-Khayyat M, Varasteh A, Chamani J, Iranshahi M, Abnous K, Saberi MR (2015). Preparation, characterization and molecular modeling of PEGylated human growh hormone with agonist activity. International Journal of Biological Macromolecules, 80, 400-409.

130- Zamani Taghizadeh Rabe S, Iranshahi M, Mahmoudi M (2016). In vitro anti-inflammatory and immunomodulatory properties of umbelliprenin and methyl galbanate. Journal of Immunotoxicology, 13, 209-216.

131- Iranshahi M, Rezaee R, Parhiz H, Roohbakhsh A, Soltani F (2015). Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin. Life Sciences, 137, 125-132.

132- Mahdian D, Iranshahy M, Shakeri A, Hoseini A, Yavari H, Nazemi M, Iranshahi M (2015). Cytotoxicity evaluation of extracts and fractions of five marine sponges from the Persian Gulf and HPLC fingerprint analysis of cytotoxic extracts. Asian Pacific Journal of Tropical Biomedicine, 5, 896-901.

133- Mousavi SH, Davari A, Iranshahi M, Sabouri-Rad S, Tayarani-Najaran Z (2015). Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna Journal of Phytomedicine, 5, 520-530.

134- Tabrizian K, Yaghoobi NS, Iranshahi M, Shahraki J, Rezaee R, Hashemzaei M (2015). Auraptene consolidates memory, reverses scopolamine disrupted memory in passive avoidance task, and ameliorates retention deficits in mice. Iranian Journal of Basic Medical Sciences, 18, 1014-1019.

135- Khazdair MR, Boskabady MH,  Kiyanmehr M, Hashemzehi M, Iranshahi M (2015). The Inhibitory Effects of Ferula assafoetida on Muscarinic Receptors of Guinea-Pig Tracheal Smooth Muscle. Jundishapur Journal of Natural Pharmaceutical Products, 10, 1-6 (e20008).

136- Mahmoudvand M, Moharramipour S, Iranshahi M (2015). Psyche, art. No. 453701.

137- Akaberi M, Iranshahy M, Iranshahi M (2015). Review of the traditional uses, phytochemistry, pharmacology and toxicology of giant fennel (Ferula communis L. subsp. communis). Iranian Journal of Basic Medical Sciences, 18, 1049-1062.

138- Rezaie M, Farhoosh R, Pham N, Quinn RJ, Iranshahi M (2016). Dereplication of antioxidant compounds in Bene (Pistacia atlantica subsp. mutica) hull using a multiplex approach of HPLC-DAD, LC-MS and 1H NMR techniques. Journal of Pharmaceutical and Biomedical Analysis, 117, 352-362.

139- Iranshahi M, Chini MG, Masullo M, Sahebkar A, Javidnia A, Chitsazian-Yazdi M, Pergola C, Koeberle A, Werz O, Pizza C, Terracciano S, Piacente S, Bifulco G (2015). Can small modifications of natural pan-inhibitors modulate the biological selectivity? The case of curcumin prenylated derivatives acting as HDAC or mPGES-1 inhibitors. Journal of Natural Products, 78, 2867-2879.

140- Kasaian J, Mosaffa F, Behravan J, Masullo M, Piacente S, Iranshahi M (2016). Modulation of Multidrug Resistance Protein 2 Efflux in the Cisplatin Resistance Human Ovarian Carcinoma Cells A2780/RCIS by Sesquiterpene Coumarins. Phytotherapy Research, 30, 84-89.

141- Iranshahy M, Tayarani-Najaran Z, Kasaian J, Ghandadi M, Emami SA, Asili J, Chandran JM, Schneider B, Iranshahi M (2016). Highly oxygenated sesquiterpene lactones from Cousinia aitchisonii and their cytotoxic properties: rhaserolide induces apoptosis in human T lymphocyte (Jurkat) cells via the activation of c-Jun N-terminal kinase phosphorylation. Phytoherapy Research, 30, 222-226.

142- Roohbakhsh A, Iranshahy M, Iranshahi M (2016). Glycyrrhetinic acid and its derivatives: Anti-cancer and cancer chemopreventive properties, mechanisms of action and structure-cytotoxic activity relationship. Current Medicinal Chemistry, 23, 498-517.

143- Cheragi O, Dehghan G, Mahdavi M, Rahbarghazi R, Rezabakhsh A, Nozad Charoudeh H, Iranshahi M, Montazersaheb S (2016). Potent anti-angiogenic and cytotoxic effect of conferone on human colorectal adenocarcinoma HT-29 cells. Phytomedicine, 23, 398-405.

144- Ghanbarabadi M, Iranshahi M, Amoueian S, Mehri S, Motamedshariaty VS, Mohajeri SA (2016). Neuroprotective and memory enhancing effects of auraptene in a rat model of vascular dementia: Experimental study and histopathological evaluation.  Neuroscience Letters, 621, 13-21.

145- Akaberi M, Iranshahi M, Mehri S (2016). Molecular signaling pathways behind the biological effects of Salvia species diterpenes in neuropharmacology and cardiology. Phytotherapy Research, 30, 878-893.

146- Eghbaliferiz S, Iranshahi M (2016). Prooxidant activity of polyphenols, flavonoids, anthocyanins and carotenoids: Updated review of mechanisms and catalyzing metals. Phytotherapy Research, 30, 1379-1391.

147- Hashemzaei M, Khandan Barani A, Iranshahi M, Rezaee M, Tsarouhas K, Tsatsakis M, Wilks MF, Tabrizian K (2016).  Effects of resveratrol on carbon monoxide-induced cardiotoxicity in rats. Environmental Toxicology and Pharmacology, 46, 110-115.

148- Boghrati Z, Naseri M, Rezaei M, Pham N, Quinn RJ, Tayarani-Najaran Z, Iranshahi M (2016). Tyrosinase inhibitory properties of phenylpropanoid glycosides and flavonoids from Teucrium polium L. var. gnaphalodes. Iranian Journal of Basic Medical Sciences, 19, 804-811.

149- Tourchi-Roudsari M, Arslan A, Iranshahi M (2016). Biological effects of arctiin from some medicinal plants of asteraceae family. American Journal of Biology and Life Sciences, 4, 41-47.

150- Rasti H, Parivar K, Baharara J, Iranshahi M, Namvar F (2016).  Chitosan extracted from the Persian Gulf chiton shells: Induction of apoptosis in liver cancer cell line. Iranian Journal of Fisheries Sciences, 15, 1362-1378.

151- Aldaghi L, Rad A, Arab A, Kasaian J, Iranshahi M, Sadr AS, Soltani F (2016). In silico and in vitro evaluation of cytotoxic activities of farnesiferol C and microlobin on MCF-7, HeLa and KYSE cell lines. Drug Research, 66, 532-538.

152- Nejad Ebrahimi S, Bagheri-Zomorrodi Z, Shakeri A, Iranshahy M, Masullo M, Piacente S, Iranshahi M (2016). The absolute configuration and cytotoxic properties of roehybridine β-N-oxide. Natural Product Communications, 11, 1813-1816.

153- Khameneh B, Saberi MR, Hassanzadeh-Khayyat M, Mohammadpanah H, Ghandadi M, Iranshahi M, Baratian M, Jaafari MR (2016). Evaluation of physicochemical and stability properties of human growth hormone upon enzymatic PEGylation. Journal of Applied Bioscience, 14, 257-264.

154- Kasaian J, Asili J, Iranshahi M (2016). Sulphur-containing compounds in the essential oil of Ferula alliacea roots and their mass spectral fragmentation patterns. Pharmaceutical Biology, 54, 2264-2268.

155- Askari VR, Rezaee SA, Abnous K, Iranshahi M, Boskabady MH (2016). The influence of hydro-ethanolic extract of Portulaca oleracea L. on Th1/Th2 balance in isolated human lymphocytes. Journal of Ethnopharmacology, 194, 1112-1121.

156- Saboor-Maleki S, Rassouli FB, Matin MM, Iranshahi M (2017). Auraptene attenuates malignant properties of esophageal stem-like cancer cells. Technology in Cancer Research and Treatment. 16, 519-527.

157- Sattar Z, Iranshahi M (2017). Phytochemistry and Pharmacology of Ferula persica Boiss.: A review. Iranian Journal of Basic Medical Sciences, 20, 1-8.

158- Rasti H, Parivar K, Baharara J, Iranshahi M, Namvar F (2017). Chitin from the mollusc chiton: extraction, characterization and chitosan preparation. Iranian Journal of Pharmaceutical Research, 16, 366-379.

159- Roohbakhsh A, Karimi G, Iranshahi M (2017). Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review. Biomedicine & Pharmacotherapy, 91, 31-42.

160- Taleghani A, Nasseri MA, Iranshahi M (2017). Synthesis of dual-action parthenolide prodrugs as potent anticancer agents. Bioorganic Chemistry, 71, 128-134.

161- Hashemzaei M, Abdollahzadeh M, Iranshahi M, Golmakani E, Rezaee R, Tabrizian K (2017). Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. Journal of Complementary and Integrative Medicine, 20160066.

162- Shour S, Iranshahy M, Pham N, Quinn RJ, Iranshahi M (2017). Dereplication of cytotoxic compounds from different parts of Sophora pachycarpa using an integrated method of HPLC, LC-MS and 1H-NMR techniques. Natural Product Research, 31, 1270-1276.

163- Iranshahy M, Javadi B, Iranshahi M, Jahanbakhsh SP, Mahyari S, Hassani FV, Karimi G (2017). A review of traditional uses, phytochemistry and pharmacology of Portulaca oleracea L. Journal of Ethnopharmacology, 205, 158-172.

164- Lee JC, Shin EA, Kim B, Kim BI, Chitsazian-Yazdi M, Iranshahi M, Kim SH (2017). Auraptene induces apoptosis via myeloid cell leukemia 1-mediated activation of caspases in PC3 and DU145 prostate cancer cells. Phytotherapy Research, 31, 891-898.

165- Mollazadeh S, Neshati V, Fazly Bazzaz BS, Iranshahi M, Mojarrad M, Naderi-Meshkin H, Kerachian MA (2017). Standardized Sophora pachycarpa root extract enhances osteogenic differentiation in adipose-derived human mesenchymal stem cells. Phytotherapy Research, 31, 792-800.

166- Mohadeszadeh M, Iranshahi M (2017). Recent advances of in the catalytic one-pot synthesis of flavonoids and chromones. Mini-Reviews in Medicinal Chemistry, 17, 1377-1397.

167- Sattar Z, Iranshahi M (2017). Phytochemistry and Pharmacology of Ferula hermonis Bioss. – A review. Drug Research, 67, 437-446.

168- Jelodarian Z, Shokoohinia Y, Rashidi M, Ghiasvand N, Hosseinzadeh L, Iranshahi M (2017). New polyacetylenes from Echinophora cinerea (Bioss.) Hedge et Lemond. Natural Product Research, 19, 2256-2263.

169- Mousavi M, Haddad F, Rassouli FB, Iranshahi M, Soleymanifard S (2017). Synergy between auraptene, ionizing radiation, and anticancer drugs in colon adenocarcinoma. Phytotherapy Research, 31, 1369-1375.

170- Vakili T, Iranshahi M, Arab H, Riahi B, Mohammadian Roshan N, Karimi G (2017). Safety evaluation of auraptene in rats in acute and subacute toxicity studies. Regulatory Toxicology and Pharmacology, 91, 159-164.

171- Rashtbari S, Dehghan G, Yekta R, Jouyban A, Iranshahi M (2017). Effects of resveratrol on the structure and catalytic fuction of bovine liver catalase (BLC): Spectroscopic and theoretical studies. Advanced Pharmaceutical Bulletin, 7, 349-357.

172- Vahedi MM, Mahdian D, Jafarian AH, Iranshahi M, Esmailzadeh M, Ghorbani A (2018). Toxicity assessment of Ferula gummosa administration during pregnancy, lactation, and juvenile period in rat. Drug and Chemical Toxicology, 41, 199-205.

173- Shakeri A, Amini E, Asili J, Masullo M, Piacente S, Iranshahi M (2018). Screening of several biological activities induced by different sesquiterpene lactones isolated from Centaurea behen L. and Rhaponticum repens (L.) Hidalgo.  Natural Product Research, 32, 1436-1440.

174- Soltani S, Amin G, Salehi-Sourmaghi MH, Schneider B, Lorenz S, Iranshahi M (2018). Sulfur-containing derivatives from the roots of Ferula latisecta and their cytotoxic activities. Fitoterapia, 124, 108-112.

175- Khajeh MA, Dehghan G, Dastmalchi S, Shaghaghi M, Iranshahi M (2018). Spectroscopic profiling and computational study of the binding of tschimgine: A natural monoterpene derivative, with calf thymus DNA. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 192, 384-392.

176- Shakeri A, Masullo M, D’Urso G, Iranshahi M, Montoro P, Pizza C, Piacente S (2018). In depth chemical investigation of Glycyrrhiza triphylla Fishc roots guided by a preliminary HPLC-ESIMS profiling. Food Chemistry, 248, 128-136.

177- Taleghani A, Iranshahi M, Naseri MA (2018).
Phytochemical Screening and Green Biosynthesis of Silver Nanoparticles Using Unripe Fruit of Ziziphus Vulgaris, Journal of Nanostructures, 8, 300-306.

178- Naseri M, Emami SA, Asili J, Tayarani-Najaran Z, Dehghan G, Schneider B, Iranshahi M (2018). Rupestrines A-D, alkaloids from the aerial parts of Corydalis rupestris. Bioorganic Chemistry, 77, 651-659.

179- Akbari M, Askari Zadeh A, Sadri K, Iranshahi M, Jaafari MR, Khamesipour A, Badiee A (2018). Antileishmanial activity of nanoliposomes containing curcumin in vitro and in vivo. Journal of Dermatology and Cosmetic, 8, 204-217.

180- Fazly Bazzaz BS, Khameneh B, Namazi N, Iranshahi M, Davoodi D, Golmohammadzadeh S (2018). Solid lipid nanoparticles carrying Eugenia caryophyllata essential oil: the novel nanoparticulate systems with broad-spectrum antimicrobial activity. Letters in Applied Microbiology, 66, 506-513.

 

181- Mousavi M, Haddad F, Matin MM, Iranshahi M, Rassouli FB (2018). Efficacy of hyperthermia in human colon adenocarcinoma cells is improved by auraptene. Biochemistry and Cell Biology, 96, 32-37.

182- Daneshmand S, Jaafari MR, Movaffagh J, Malaekeh-Nikoiei B, Iranshahi M, Sededian Mogaddam A, Tayarani-Najaran Z, Golmohammadzadeh S (2018). Preparation, characterization, and optimization of auraptene-loaded solid lipid nanoparticles as a natural anti-inflammatory agent: In vivo and in vitro evaluations. Colloids and surfaces B: Biointerfaces, 164, 332-339.

183- Eghbaliferiz S, Emami SA, Tayarani-Najaran Z, Iranshahi M, Shakeri A, Hohmann J, Asili J (2018). Cytotoxic diterpene quinones from Salvia tebesana Bunge.  Fitoterapia, 128, 97-101.

184- Neshati V, Mollazadeh S, Fazly Bazzaz BS, Iranshahi M, Mojarrad M, Naderi-Meshkin M, Kerachian MA (2018). Cardiogenic effects of characterized Geum urbanum extracts on adipose-derived human mesenchymal stem cells. Biochemistry and Cell Biology, 96, 610-618.

185- Iranshahi M, Rezaee R, Najaf Najafi M, Haghbin A, Kasaian J (2018). Cytotoxic activity of the genus Ferula (Apiaceae) and its bioactive constituents. Avicenna Journal of Phytomedicine, 8, 296-312.

186- Rameshrad M, Imenshahidi M, Razavi BM, Iranshahi M, Hosseinzade H (2018). Bisphenol A vascular toxicity: Protective effect of Vitis vinifera (grape) seed extract and resveratrol. Phytotherapy Research, 32, 2396-2407.

187- Iranshahy M, Iranshahi M, Abtahi SR, Karimi G (2018). The role of nuclear factor erythroid 2-related factor 2 in hepatoprotective activity of natural products: A review. Food and Chemical Toxicology, 120, 261-276.

188- Naserian M, Ramazani E, Iranshahi M, Tayarani-Najaran Z (2018). The role of SAPK/JNK pathway in the synergistic effects of metformin and dacarbazine on apoptosis in Raji and Ramos lymphoma cells. Current Molecular Pharmacology, 11, 336-342.

189- Boghrati Z, Iranshahi M. Ferula species: A rich source of antimicrobial compounds. Journal of Herbal Medicine, 16, 100244.

190- Charmforoshan E, Karimi E, Oskoueian E, Es-Haghi A, Iranshahi M (2019). Inhibition of human breast cancer cells (MCF-7 cell line) growth via cell proliferation, migration, and angiogenesis by auraptene of Ferula szowitsiana root extract. Journal of Food Measurement and Characterization, 13, 2644-2653.

191- Jahan Yazdi A, Javanshir S, Soukhtanloo M, Jalili-Nik M, Jafarian AH, Iranshahi M, Hasanpour M, Khatami SM, Hosseini A, Amiri MS, Ghorbani A (2019). Acute and sub-acute toxicity evaluation on the root extract of Rheum turkestanicum Janisch. Drug and Chemical Toxicology, in press

192- Askari VR, Baradaran Rahimi V, Assaran A, Iranshahi M, Boskabady MH (2019). Evaluation of the anti-oxidant and anti-inflammatory effects of the methanolic extract of Ferula szowitsiana root on PHA-induced inflammation in human lymphocytes. Drug and Chemical Toxicology, in press

 193- Farhadi F, Khameneh B, Iranshahi M, Iranshahy M (2019). Antibacterial activity of flavonoids and their structure–activity relationship: An update review. Phytotherapy Research, 33, 13-40.

194- Soltani S, Amin G, Salehi-Sourmaghi MH, Iranshahi M (2019). Histone deacetylase inhibitory and cytotoxic activities of the constituents from the roots of three species of Ferula. Iranian Journal of Basic Medical Sciences, 22, 93-98.

195- Mohtashami L, Ghows N, Tayarani-Najaran Z, Iranshahi M (2019). Galbanic acid-coated Fe3O4 magnetic nanoparticles with enhanced cytotoxicity to prostate cancer cells. Planta Medica 85, 169-178.

196- Sattar Z, Iranshahy M, Iranshahi M (2019). Lutein is Four Times More Stable in Sunflower Oil than Olive Oil at 40 °C. (2019) European Journal of Lipid Science and Technology, 121 (2), art. no. 1800126.

197- Boozari M, Soltani S, Iranshahi M (2019). Biologically active prenylated flavonoids from the genus Sophora and their structure–activity relationship—A review. Phytotherapy Research, 33, 546-560.

198- Mirakabad HZ, Farsi M, Shafaroudi SM, Bagheri A, Iranshahi M, Moshtaghi N (2019). Comparison the effect of ferutinin and 17β-estradiol on bone mineralization of developing zebrafish (Danio rerio) Larvae. International Journal of Molecular Sciences, 20, art. no. 1507.

199-  Boozari M, Nejad Ebrahimi S, Soltani S, Tayarani-Najaran Z, Emami SA, Asili J, Iranshahi M (2019). Absolute configuration and anti-cancer effect of prenylated flavonoids and flavonostilbenes from Sophora pachycarpa: Possible involvement of Wnt signaling pathway. Bioorganic Chemistry, 85, 498-504.

200- Akaberi M, Danton O, Tayarani-Najaran Z, Asili J, Iranshahi M, Emami SA, Hamburger M (2019). HPLC-based activity profiling for antiprotozoal compounds in the endemic iranian medicinal plant Helichrysum oocephalum. Journal of Natural Products, 82, 958-969.

201- Shakeri A, Masullo M, Bottone A, Asili J, Emami SA, Piacente S, Iranshahi M (2019). Sesquiterpene lactones from Centaurea rhizantha C.A. Meyer. Natural Product Research, 33, 2016-2023.

202- Farhadi F, Soltani S, Saberi S, Iranshahi M (2019). A qHNMR method for simultaneous quantification of terpenoids from Ferula ovina (Boiss.) Boiss roots. Journal of Pharmaceutical and Biomedical Analysis, 172, 120-125.

203- Nik, ME, Momtazi-Borojeni AA, Zamani P, Navashenaq JG, Iranshahi M, Jaafari MR, Malaekeh-Nikouei B (2019). Targeted-nanoliposomal combretastatin A4 (CA-4) as an efficient antivascular candidate in the metastatic cancer treatment. Journal of Cellular Physiology, 234, 14721-14733.

204- Zamani S, Emami SA, Iranshahi M, Zamani Taghizadeh Rabe S, Mamoudi M (2019).  Sesquiterpene fractions of Artemisia plants as potent inhibitors of inducible nitric oxide synthase and cyclooxygenase-2 expression. Iranian Journal of Basic Medical Sciences, 22, 774-780.

205- Iranshahy M, Farhadi F, Paknejad P, Zareian P, Iranshahi M, Karami M, Abtahi SR (2019). Gummosin, a sesquiterpene coumarin from Ferula assa-foetida is preferentially cytotoxic to human breast and prostate cancer cell lines. Avicenna Journal of Phytomedicine, 9, 446-453.

206- Jafari A, Teymouri M, Ebrahimi Nik M, Abbasi A, Iranshahi M, Hanafi-Bojd MY, Hafari MR (2019). Interactive anticancer effect of nanomicellar curcumin and galbanic acid combination therapy with some common chemotherapeutics in colon carcinoma cells.  Avicenna Journal of Phytomedicine, 9, 237-247.

207- Ebrahimi Nik M, Malaekeh-Nikouei B, Amin M, Hatamipour M, Teymouri M, Sadeghnia HR, Iranshahi M, Jaafari MR (2019). Liposomal formulation of Galbanic acid improved therapeutic efficacy of pegylated liposomal Doxorubicin in mouse colon carcinoma. Scientific Reports, 9, 9527.

208- Sajjadi M, Karimi E, Oskoueian E, Iranshahi M, Neamati A (2019). Galbanic acid: Induced antiproliferation in estrogen receptor-negative breast cancer cells and enhanced cellular redox state in the human dermal fibroblasts. Journal of Biochemical and Molecular Toxicology, 33, e22402.

209- Farhadi F, Asili J, Iranshahy M, Iranshahi M (2019). NMR-based metabolomic study of asafetida. Fitoterapia, 139, 104361.

210- Tavakkoli A, Iranshahi M, Hasheminezhad SH, Hayes AW, Karimi G (2019). The neuroprotective activities of natural products through the Nrf2 upregulation. Phytotherapy Research, 33, 2256-2273.

 211- Etemad L, Zamani M, Iranshahi M, Roohbakhsh A (2019). The protective effect of auraptene against oxidative stress and pentylenetetrazol-induced chemical kindling in mice. Iranian Journal of Basic Medical Sciences, 18, 1395-1402.

212- Jalilzadeh, N., Samadi, N., Salehi, R., Dehghan, G., Iranshahi, M., Dadpour, M.R., Hamishehkar, H. (2020). Novel nano-vehicle for delivery and efficiency of anticancer auraptene against colon cancer cells. Scientific Reports, 10 (1), art. no. 1606.

213- Baradaran Rahimi, V., Rajabian, A., Rajabi, H., Mohammadi Vosough, E., Mirkarimi, H.R., Hasanpour, M., Iranshahi, M., Rakhshandeh, H., Askari, V.R. (2020).The effects of hydro-ethanolic extract of Capparis spinosa (C. spinosa) on lipopolysaccharide (LPS)-induced inflammation and cognitive impairment: Evidence from in vivo and in vitro studies. Journal of Ethnopharmacology, 256, art. no. 112706.

214- Afkhami-Poostchi, A., Mashreghi, M., Iranshahi, M., Matin, M.M. (2020).Use of a genetically engineered E. coli overexpressing β-glucuronidase accompanied by glycyrrhizic acid, a natural and anti-inflammatory agent, for directed treatment of colon carcinoma in a mouse model. International Journal of Pharmaceutics, 579, art. no. 119159.

215- Maleki, S., Dehghan, G., Sadeghi, L., Rashtbari, S., Iranshahi, M., Sheibani, N. (2020). Surface plasmon resonance, fluorescence, and molecular docking studies of bovine serum albumin interactions with natural coumarin diversin. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 230, art. no. 118063.

216- Eidi, S., Iranshahi, M., Mohammadinejad, A., Mohsenzadeh, M.S., Farhadi, F., Mohajeri, S.A.(2020).Selective isolation of sesquiterpene coumarins from asafoetida using dummy molecularly imprinted solid phase extraction method. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1138, art. no. 121943.

217- Rashtbari, S., Khataee, S., Iranshahi, M., Moosavi-Movahedi, A.A., Hosseinzadeh, G., Dehghan, G. (2020). Experimental investigation and molecular dynamics simulation of the binding of ellagic acid to bovine liver catalase: Activation study and interaction mechanism. International Journal of Biological macromolecules, 143, pp. 850-861.

218- Hasanpour, M., Saberi, S., Iranshahi, M. (2020). Metabolic Profiling and Untargeted 1 H-NMR-Based Metabolomics Study of Different Iranian Pomegranate (Punica granatum) Ecotypes. Planta Medica, 86 (3), pp. 212-219.

219- Tazik, Z., Rahnama, K., Iranshahi, M., White, J.F., Soltanloo, H. (2020). A new species of Pithoascus and first report of this genus as endophyte associated with Ferula ovina. Mycoscience, 61, 145-150.

Conference presentations:

 

1- Ghahremani MH, Shabani M, Monsef HR, Iranshahi M. Ostad SN. The effect of  essential  oil  of  Lavandula  officinalis  on  Dopaminergic  system  evaluated  by  apomorohine  induced  licking  behavior  in  rat. 5th International Congress on  Traditional  Asian  Medicine, Halle (Saale), Germany, 18-24, August, 2002.

2-  Azizi E, Parvinroo  Sh, Iranshahi  M,  Amin  GR. Effect  of  lycopene  on  proliferation  of  human   breast  cancer  T47D  cells  and  its  tamoxifen  resistant  subtype. CNIO  Cancer  Conference, Madrid, Spain, 17-19 March, 2003.

3- Iranshahi M, Shafiee A, Amin GR. Phytochemical study on two varieties of Ferula persica Willd. (latisecta and persica), 3th International Congress of Health, Environment & Natural Products, Mashhad, Iran, 25-28 Sep., 2004 .

4- Azizi E, Mazidi T, Iranshahi M, Amin GR. Synergistic effects of tamoxifen and extract of Nerium oleander L. on proliferation of T47D and TAMR-6 cells, Toxicology and Applied Pharmacology, 197 (3): 311-311, 699, 15 Jun., 2004.

5- Ostad SN, Monsef HR, Iranshahi M, Mehdinejad Khameneh K. Analgesic and anti-inflammatory effect of Vasicinone and two other derivatives in mice, Proceeding of 51th Annual Congress of the Society for Medicinal Plant Research, Kiel, Germany, 2003.

6- Iranshahi M. Application of two dimensional NMR spectroscopy for structure elucidation of natural products. The 10th Iranian Pharmaceutical Sciences Conference, Tehran, Iran, 2006.

7- Behravan J, Mosaffa F, Karimi G, Iranshahi M. Antigenotoxic effects of Satureja hortensis on rat lymphodytes exposed oxidative stress. The 54th international congress and annual meeting of the society for medicinal plant research, Helsinki, Finland, 2006.

8- Shahverdi AR, Iranshahi M. Ultra low concentrations of sophoraflavanone G from Sophora pachycarpa C. Meyer enhanced the antibacterial activity of gentamycin aginst Staphylococcus aureusThe 54th international congress and annual meeting of the society for medicinal plant research, Helsinki, Finland, 2006.

9- Iranshahi M, Schneider B, Mojarab M, Sadeghian H, Hanafi-Bojd MY. Persicaosides A-D, polar secondary metabolites of Ferula persica roots. The 55th international congress and annual meeting of the society for medicinal plant research, Graz, Austria, 2007.

10- Tghizadeh Rabe SZ, Mahmoudi M, Iranshahi M. Sesquiterpene derivatives isolated from Dorema kopetdaghense inhibit nitric oxide production in LPS-activated macrophages. The 9th iranian congress of biochemistry, Shiraz, Iran, 2007.

11- Iranshahi M, Sahebkar A, Takasaki M, Konoshima T, Tokuda H. Cancer chemopreventive activity of the prenylated coumarin umbelliprenin The 57th international congress and annual meeting of the society for medicinal plant research, Geneva, Switzerland, 2009.

12- Iranshahi M, Davis RA, Vu H, Pham N, Quinn RJ. Alkaloids from Erythrina vespertilio fruits. 27th international symposium on the chemistry of natural products (ISCNP27), held jointly with the 7th international conference on biodiversity (ICOB7), Brisbane, Australia, 2011