Curriculum Vitae
Soghra Mehri (Pharm.D., Ph.D of Toxicology) Ph.D of Toxicilogy Associate Professor Department of Pharmacodynamics and Toxicology School of Pharmacy, Mashhad University of Medical Sciences, Mashhad-Iran P.O. Box: 91775-1365 Phone: ++98-51-31801179 Fax: ++98-51-38823251 E-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
Education Pharm D: School of pharmacy, Mashhad University of Medical Sciences, Iran (1998-2004) Ph.D of Toxicology: Department of Pharmacodynamics and Toxicology, Mashhad University of Medical Sciences, Iran (2007-2012) Sabbatical course: Rudolf-Boehm-Institute of Pharmacology and Toxicology, University of Leipzig, Leipzig, Germany (2011 January- 2011 July)
Research interests Neurotoxicity (Different mechanisms of induction and protection) Neuropharmacology Primary cell culture Cellular and molecular signaling pathways Evaluation of biologic effects of herbal medicine
Publications 1) Karimi, Gh., Hassanzadeh, M. and Mehri, S. Protective Effect of Rosmarinus officinalis L. Essential Oil against Free Radical-Induced Erythrocyte Lysis. Iranian Journal of Pharmaceutical Sciences, 2005, 1, 231-236. 2) Karimi, Gh., Hassanzadeh, M. and Mehri, S. Protective Effects of Silymarin against Free Radical-Induced Erythrocyte Lysis. Journal of Complementary and Integrative Medicine, 2006, 3. 3) Hosseinzadeh, H., Shamsaie, F. and Mehri, S. Antioxidant Activity of Aqueous and Ethanolic Extracts of Crocus sativus L. Stigma and its Bioactive Constituents, Crocin and Safranl. Pharmacognosy Magazine, 2009, 20, 419-424. 4) Mousavi, S.H., Moallem S.A., Mehri, S. Shahsavand, Sh., Nasirli, H. and Malaekeh, B. Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form. Pharmaceutical biology, 2011, 49: 1035-1045. 5) Rasekh, H.R., Hosseinzadeh, L., Mehri, S. Kamli-Nejad, M., Aslani, M., Tanbakoosazan, F., and Almousavi, M. Safety assessment of Ocimum basilicum hydroalcholic extract in wistar rats: Acute and subchronic toxicity studies. Iranian Journal of Basic Medical Sciences, 2012, 15: 645-653. 6) Hosseinzadeh, H., Sajadi Tabasi, A., Milani Moghadam, N., Rashedinia, R. and Mehri, S. Antioxidant activity of Pistacia vera fruits, leaves and gum extracts Iranian Journal of Pharmaceutical Research, 2012, 11: 879-887. 7) Mehri, S. Abnous, Kh., Mousavi, S.H. Motamed shariaty, V. Hosseinzadeh, H. Neuroprotective effect of crocin on acrylamide-induced cytotoxiciyt in PC 12 cells. Cellular and Molecular Neurobiology, 2012, 32: 227-235. 8) Mehdizadeh, R., Khooei, A., Parizadeh, M., Mehri, S. Hosseinzadeh, H Cardioprotective Effect of Saffron Extract and Safranal in Isoproterenol-Induced Myocardial Infarction in wistar Rats. Iranian Journal of Basic Medical Sciences , 2013, 16, 56-63. 9) Badiyan, Z. Moallem S.A, Mehri, S., Shahsavand, Sh, Hadizadeh, F. Virtual screening for novel COX-2 inhibitors as antitumor agents using the ZINC database. The open Medicinal Chemistry Journal, 2012, 6: 15-19. 10) Hosseinzadeh, H., Mehri, S. Abolhassani, MM., Ramezani, M., Sahebkar, A., Abnous, K. Affinity-based target deconvolution of safranal. DARU Journal of Pharmaceutical Sciences, 2013, 20; 21(1):25. 11) Malaekeh, B. Mousavi, S.H, Shahsavand, Sh, Mehri, S., Nasirli, H and Moallem S.A. Assessment of cytotoxic properties of safranal and nanoliposomal safranal in various cancer cell lines, Phytotherapy Research , 2013 (Dec) 27(12):1868-73. 12) Hosseinzadeh, H., Mehri, S., Heshmati, A., Ramezani, M., Sahebkar, A., and Abnous, Kh. Proteomic screening of molecular targets of crocin. DARU Journal of Pharmaceutical Sciences 2014, 6; 22(1):5. 13) Abnous, K., Barati, B., Mehri, S., Masboghi Farimani, MR., Alibolandi, M., Mohammadpour, F., Ghandadi, M., Hadizadeh, F. Synthesis and molecular modeling of six novel monastrol analogues: evaluation of cytotoxicity and kinesin inhibitory activity against HeLa cell line. DARU Journal of Pharmaceutical Sciences , 2013, 19;21(1):70 14) Vahdati Hassani, F Naseri, V., Razavi, BM., Mehri, S., Abnous, K., Hosseinzadeh, H. Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus. DARU Journal of Pharmaceutical Sciences, 2014, 8; 22(1):16. 15) Mehri, S., Karami, HV. Hassani, FV. Hosseinzadeh, H. Chrysin Reduced Acrylamide-Induced Neurotoxicity in both in vitro and in vivo Assessments. Iranian Biomedical Journal 2014; 18(2):101-6. 16) Jamialahmadi, K, Arasteh, O, Matbou Riahi, M.b, Mehri, S, Riahi-Zanjani, B, Karimi, G. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environmental Toxicology and Pharmacology, 2014, 38 (1): 212-219. 17) Ghorbani, M, Mohamadpour, AH, Mehri, S, Abnous, Kh, Hassanzadeh-Khayyat, M. Proteomics screening of molecular targets of granulocyte colony stimulating factor in the mouse brain and PC12 cell line. Life Science, 2014, 108(1):44-47. 18) Rubini, P, Pagel, G, Mehri, S, Marquardt, P, Riedel, T, Illes, P. Functional P2X7 receptors at cultured hippocampal astrocytes but not neurons. Naunyn-Schmiedeberg's Archives of Pharmacology, 2014, 387(10):943-954 19) Davari, A.S, Abnous, K. Mehri, S, Ghandadi, M, Hadizadeh,F. Synthesis and biological evaluation of novel pyridine derivatives as potential anticancer agents and phosphodiesterase-3 inhibitors. Bioorganic Chemistry, 2014, 57:83-89. 20) Mehri, S, Shahi, M, Razavi, BM, Vahdati Hassani, F, Hosseinzadeh, H.
21) Ghasemi, T., Abnous, Kh., Vahdati Hassani, F., Mehri, S,. Razavi, BM. Hoseinzadeh, H, Antidepressant effect of Crocus sativus aqueous extract and its effect on CREB, BDNF, and VGF transcript and protein levels in rat hippocampus. Drug Research, 2015, 65 (7): 337-343. 22) Mehri S, Meshki MA, Hosseinzadeh H. Linalool as a neuroprotective agent against acrylamide-induced neurotoxicity in Wistar rats. Drug Chemical Toxicology, 2015, 38(2): 162-166. 23) Moallem, SA, Dehghani, N, Mehri, S, Alibolandi, M, Hadizadeh, F.Synthesis of novel 1,8-acridinediones derivatives: Investigation of MDR reversibility on breast cancer cell lines T47D and tamoxifenresistant T47D. Research in Pharmaceutical Sciences, 2015, 10 (3): 214-221. 24) Mehri, S, Abnous, K, Khooei, A, Shariaty, V.M, Hosseinzadeh, H. Crocin reduced acrylamide-induced neurotoxicity in wistar rat through inhibition of oxidative stress. Iranian Journal of Basic Medical Sciences, 2015, 18 (9): 902-908. 25) Akaberi, M, Mehri, S, Iranshahi, M. Multiple pro-apoptotic targets of abietane diterpenoids from Salvia species. Fitoterapia , 2016, 30 (6): 878-893. 26) Ghanbarabadi, M, Iranshahi, M, Amoueian, S, Mehri, S, Motamedshariaty, V.S, Mohajeri, S.A. Neuroprotective and memory enhancing effects of auraptene in a rat model of vascular dementia: Experimental study and histopathological evaluation. Neuroscience Letters, 2016, 623(3): 13-21. 27) Ghasemzadeh Rahbardar, M., Amin, B, Mehri, S, Mirnajafi-Zadeh, S.J, Hosseinzadeh, H. Effect of alcoholic extract of aerial parts of Rosmarinus officinalis L. on pain, inflammation and apoptosis induced by chronic constriction injury (CCI) model of neuropathic pain in rats. Journal of Ethnopharmacology, 2016, 194,24: 117-130. 28) Kamyar, M, Razavi, BM, Vahdati Hasani, BM, Mehri, S, Foroutanfar, A, Hosseinzadeh, H. Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism. Iranian Journal of Basic Medical Sciences. 2016, 19, 10: 1070-1079. 29) Mehri,S, Dadesh,Q, Tabeshpour,J, Vahdati Hassani,F, Karimi,Gh and Hosseinzadeh, H. Evaluation of the Neuroprotective Effect of Silymarin on Acrylamide-Induced Neurotoxicity. Jundishapur Journal of Natural Pharmaceutical Products. 2016, 11, open access. 30) Akaberi, M, Iranshahi, M, Mehri, S. Molecular Signaling Pathways Behind the Biological Effects of Salvia Species Diterpenes in Neuropharmacology and Cardiology. Phytotherapy Research (IF: 2.69 ). 2016, 30: 878-893. 31) Bostan, H.B.Mehri, S. Hosseinzadeh, H. Toxicology effects of saffron and its constituents: A review. این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت داریدIranian Journal of Basic Medical Sciences. 2017, 20: 110:121. 32) Ghasemzadeh Rahbardar, M., Amin, B, Mehri, S, Mirnajafi-Zadeh, S.J, Hosseinzadeh, H. Anti-inflammatory effects of ethanolic extract of Rosmarinus officinalis L. and rosmarinic acid in a rat model of neuropathic pain. Biomedicine and Pharmacotherapy. 2017, 86: 441-449. 33) Malayeri, S.O, Abnous, K., Arab, A., Akaberi, M., Mehri, S., Zarghi, A, Ghodsi, R. Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp90 inhibitors and anticancer agent. Bioorganic and Medicinal Chemistry. 2017, 25:1294-1302. 34) Pishavar, E., Shafiei, M., Mehri, S., Ramezani, M., Abnous, K. The effects of polyethylenimine/DNA nanoparticle on transcript levels of apoptosis-related genes. Drug and Chemical Toxicology. 2014. 1-4. 31) Heidari, S, Mehri, S, Hosseinzadeh, H. Memory enhancement and protective effects of crocin against D-galactose aging model in the hippocampus of wistar rats. Iranian Journal of Basic Medical Sciences. 2017, 20: 1250-1259. 32) Ghazavi, H, Hoseini, S, Ebrahimzadeh-Bideskan, A, Mashkani, B, Mehri, S, Ghorbani, A, Sadri, K, Mahdipour, E, Ghasemi, F, Forouzanfar, F, Hoseini, A, Pasdar, A.R, Sadeghnia, H.R., Ghayour-Mobarhan, M. Fibroblast Growth Factor Type 1 (FGF1)-Overexpressed Adipose-Derived Mesenchaymal Stem Cells (AD-MSCFGF1) Induce Neuroprotection and Functional Recovery in a Rat Stroke Model. Stem Cell Reviews and Reports. 2017, 13: 670-685. 33) Vahdati Hassani, F, Mehri, S, Abnous, K, Birner-Gruenberger, R., Hosseinzadeh, H. Protective effect of crocin on BPA-induced liver toxicity in rats through inhibition of oxidative stress and downregulation of MAPK and MAPKAP signaling pathway and miRNA-122 expression. Food and Chemical Toxicology. 2017, 107: 395-405. 34) Mohammadzadeh, N, Mehri, S, Hosseinzadeh, H. Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities. Iranian Journal of Basic Medical Sciences. 2017, 20: 538-551. 35) Shahroudi, M, Mehri, S, Hosseinzadeh, H. Anti-aging effect of nigella sativa fixed oil on d-galactose-induced aging in mice. Journal of Pharmacopuncture. 2017, 20: 29-35. 36) Ebrahimpour, S, Fazeli, M, Mehri, S, Taherianfard, M, Hosseinzadeh, H. Boswellic acid improves cognitive function in a rat model through its antioxidant activity: Neuroprotective effect of boswellic acid. Journal of Pharmacopuncture. 2017, 20: 10-17. 37) Bostan, H.B, Mehri, S, Hosseinzadeh, H. Toxicology effects of saffron and its constituents: A review. Iranian Journal of Basic Medical Sciences. 2017, 20: 110-121. 38) Vahdati Hassani, F, Abnous, K, Mehri, S. Jafarian, A, Birner-Gruenberger, R, Yazdian Robati, Hosseinzadeh, H. Proteomics and phosphoproteomics analysis of liver in male rats exposed to bisphenol A: Mechanism of hepatotoxicity and biomarker discovery. Food and Chemical Toxicology. 2018, 112: 26-38. 39) Tabeshpour, J., Mehri, S., Shaebani Behbahani, F., Hosseinzadeh, H. Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review. Phytotherapy Research. 2018, 32: 2164-2190. 40) Jahani, V., Kavousi, A., Mehri, S., Karimi, G. Rho kinase, a potential target in the treatment of metabolic syndrome. Biomedicine and Pharmacotherapy. 2018, 106: 1024-1030. 41) Makhdoumi, P., Abnous, K., Mehri, S., Etemad, L., Imenshahidi, M., Karimi, G.Oral deferiprone administration ameliorates cisplatin-induced nephrotoxicity in ratsJournal of Pharmacy and Pharmacology. 2018, 70: 1357-1368. 42) Mehri, S., Sajjadi, S.S., Tabatabai, S.M., Hosseinzadeh, H. Research Paper: Effects of Clavulanic Acid on the acquisition and reinstatement following morphine-induced conditioned place preference in mice. Basic and Clinical Neuroscience. 2018, 9: 229-236. 43) Yousefsani, B.S., Mehri, S., Pourahmad, J., Hosseinzadeh, H. Crocin prevents sub-cellular organelle damage, proteolysis and apoptosis in rat hepatocytes: A justification for its hepatoprotection. Iranian Journal of Pharmaceutical Research. 2018, 17: 553-562. 44) Heidari, S., Mehri, S., Shariaty, V., Hosseinzadeh, H. Preventive effects of crocin on neuronal damages induced by D-galactose through AGEs and oxidative stress in human neuroblastoma cells (SH-SY5Y). Journal of Pharmacopuncture. 2018, 21: 18-25. 45) Rahbardar, M.G., Amin, B., Mehri, S., Mirnajafi-Zadeh, S.J., Hosseinzadeh, H. Rosmarinic acid attenuates development and existing pain in a rat model of neuropathic pain: An evidence of anti-oxidative and anti-inflammatory effects. Phytomedicine. 2018, 40: 59-67. 46) Forouzanfar, F., Amin, B., Ghorbani, A., Ghazavi, H., Ghasemi, F., Sadri, K., Mehri, S., Sadeghnia, H.R., Hosseinzadeh, H. New approach for the treatment ofneuropathic pain: Fibroblast growth factor 1 gene-transfected adipose-derived mesenchymal stem cellsEuropean Journal of Pain. 2018, 22: 295-310. 47) Mohammadzadeh, L., Mehri, S., Hosseinzadeh, H. Protective effect of grape seed extract against acrylamide-induced neurotoxicity in vitro and in vivo. Journal of Reports in Pharmaceutical Sciences. 2018, 7: 344-356. 48) Shoja, M., Mehri, S., Amin, B., Askari, V.R., Hosseinzadeh, H. The prophylactic and therapeutic effects of saffron extract and crocin on ethanol withdrawal syndrome in mice Journal of Pharmacopuncture. 2018, 21: 277-283. 49) Kianfar, M., Nezami, A., Mehri, S., Hosseinzadeh, H., Hayes, A.W., Karimi, G.The protective effect of fasudil against acrylamide-induced cytotoxicity in PC12 cellsDrug and Chemical Toxicology. 2018. 50) Asghari, A., Hosseini, M., Beheshti, F., Shafei, M.N., Mehri, S. Inducible nitric oxide inhibitor aminoguanidine, ameliorated oxidative stress, interleukin-6 concentration and improved brain-derived neurotrophic factor in the brain tissues of neonates born from titanium dioxide nanoparticles exposed rats. Journal of Maternal-Fetal and Neonatal Medicine. 2019, 32: 3962-3973. 51) Amiri Tehranizadeh, Z., Sankian, M., Fazly Bazzaz, B.S., Chamani, J., Mehri, S., Baratian, A., Saberi, M.R. The immunotoxin activity of exotoxin A is sensitive to domain modifications. International Journal of Biological Macromolecules. 2019, 134: 1120-1131. 52) Zirak, M.R., Mehri, S., Karimani, A., Zeinali, M., Hayes, A.W., Karimi, G. Mechanisms behind the atherothrombotic effects of acrolein, a review. Food and Chemical Toxicology. 2019, 129: 38-53. 53) Tabeshpour, J., Mehri, S., Abnous, K., Hosseinzadeh, H. Neuroprotective Effects of Thymoquinone in Acrylamide-Induced Peripheral Nervous System Toxicity Through MAPKinase and Apoptosis Pathways in Rat. Neurochemical Research. 2019, 44: 1101-1112. 54) Dehghani, S., Mehri, S., Hosseinzadeh, H.The effects of crataegus pinnatifida (Chinese hawthorn) on metabolic syndrome: A review. Iranian Journal of Basic Medical Sciences. 2019, 22: 460-468. 55) Silakhori, S, Hosseinzade,h, Shabani Behbahani, F, Mehri, S. Neuroprotective effect of clavulanic acid on Trimethyltin (TMT)-induced cytotoxicity in PC12 cells. Drug and chemical. 2019, 4: 187-193. 56) Badibostan, H., Mehri, S., Mohammadi, E., Hosseinzadeh, H. Protective effect of thymoquinone on D-galactose-induced aging in mice. Jundishapur Journal of Natural Pharmaceutical Products. 2019, 14: e13911. 57) Adabizadeh, M., Mehri, S., Rajabpour, M., Abnous, K., Rashedinia, M., Hosseinzadeh, H. The effects of crocin on spatial memory impairment induced by hyoscine: Role of NMDA, AMPA, ERK and CaMKII proteins in rat hippocampus. Iranian Journal of Basic Medical. 2019, 22: 601-609. 58) Karimani, A., Hosseinzadeh, H., Mehri, S., Jafarian, A.H., Kamali, S.A., Mohammadpour, A., Karimi, G. Histopathological and biochemical alterations in non-diabetic and diabetic rats following acrylamide treatment. Toxin Reviews. 2019, 59) Shirani, K., Riahi Zanjani, B., Mehri, S., Razavi-Azarkhiavi, K., Badiee, A., Hayes, A.W., Giesy, J.P., Karimi, G.miR-155 influences cell-mediated immunity in Balb/c mice treated with aflatoxin M1. Drug and Chemical Toxicology. 2019. 60) Amin, B., Avaznia, M., Noorani, R., Mehri, S., Hosseinzadeh, H. Upregulation of glutamate transporter 1 by clavulanic acid administration and attenuation of allodynia and hyperalgesia in neuropathic rats. Basic and Clinical Neuroscience. 2019: 345-354. 61) Bagherpasand, N., Mehri, S., Shahroudi, M., Tabatabai, S.M., Khezri, A, Fathi, M., Abnous, K., Imenshahidi, M., Hosseinzadeh, H. Effect of topiramate on morphine-induced conditioned place preference (Cpp) in rats: Role of erk and creb proteins in hippocampus and cerebral cortex. Iranian Journal of Pharmaceutical Research. 2019, 18: 2000-2010. 62) Tavakkoli, A., Abnous, K., Vahdati Hassani, F., Hosseinzadeh, H., Birner-Gruenberger, R., Mehri, S. Alteration of protein profile in cerebral cortex of rats exposed to bisphenol a: a proteomics study. NeuroToxicology. 2020, 78: 1-10. 63) Tabeshpour, J., Mehri, S., Abnous, K., Hosseinzadeh, H. Role of Oxidative Stress, MAPKinase and Apoptosis Pathways in the Protective Effects of Thymoquinone Against Acrylamide-Induced Central Nervous System Toxicity in Rat Neurochemical Research. 2020, 45: 254-267. 64) Barangi, S., Mehri, S., Moosavi, Z., Hayes, A.W, Reiter, R.J., Cardinali, D.P., Karimi, G. Melatonin inhibits Benzo(a)pyrene-Induced apoptosis through activation of the Mir-34a/Sirt1/autophagy pathway in mouse liver. Ecotoxicology and Environmental Safety. 2020, 196. 65) Alavi, M.S., Fanoudi, S., Ghasemzadeh Rahbardar, M., Mehri, S., Hosseinzadeh, H. An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities. Phytotherapy Research, 2021, 35(3), pp. 1313-1328. 66) Oskouei, Z., Mehri, S., Kalalinia, F., Hosseinzadeh, H. Evaluation of the effect of thymoquinone in d-galactose-induced memory impairments in rats: Role of MAPK, oxidative stress, and neuroinflammation pathways and telomere length. Phytotherapy Research , 2021, 35(4), pp. 2252-2266. 67) Shirani, K., Riahi Zanjani, B., Mehri, S., Giesy, J.P., Karimi, G. miR-155 influences cell-mediated immunity in Balb/c mice treated with aflatoxin M1. Drug and Chemical Toxicology, 2021, 44(1), pp. 39-46. 68) Yousefsani, B.S., Mehri, S., Pourahmad, J., Hosseinzadeh, H. Protective effect of crocin against mitochondrial damage and memory deficit induced by beta-amyloid in the hippocampus of rats. Iranian Journal of Pharmaceutical Research, 2021, 20(2), pp. 79-94 69) Karimani, A., Hosseinzadeh, H., Mehri, S., Hooshang Mohammadpour, A., Karimi, G. Histopathological and biochemical alterations in non-diabetic and diabetic rats following acrylamide treatment. Toxin Reviews, 2021, 40(3), pp. 277-284. 70) Esmaili-Shahzade-Ali-Akbari, P., Hosseinzadeh, H., Mehri, S.. Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins.NeuroToxicology, 2021, 84, pp. 64-72. 71) Heidari, S., Mehri, S., Hosseinzadeh, H. The genus Glycyrrhiza (Fabaceae family) and its active constituents as protective agents against natural or chemical toxicities. Phytotherapy Research , 2021, 35(12), pp. 6552-6571. 72) Sepahi S, Soheili ZS, Tavakkol-Afshari J, Mehri S, Hosseini SM, Mohajeri SA, et al. Retinoprotective Effects Of Crocin And Crocetin via Anti-Angiogenic Mechanism in High Glucose-Induced Human Retinal Pigment Epithelium Cells. Current molecular pharmacology, 2021;14(5):883-93. 73 Yarmohammadi F, Mehri S, Najafi N, Salar Amoli S, Hosseinzadeh H. The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review. Iranian Journal of Basic Medical Sciences , 2021;24(3):280-92. 74) Ghasemzadeh Rahbardar M, Cheraghi Farmad H, Hosseinzadeh H, Mehri S, Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats. Iranian Journal of Basic Medical Sciences , 2021;24(8):1041-9. 75) Khodaei, M., Mehri, S., Pour, S.R. Hayes, A.W., Karimi, G. The protective effect of chemical and natural compounds against vincristine-induced peripheral neuropathy (VIPN). Naunyn-Schmiedeberg's Archives of Pharmacology, 2022, 395(8), pp. 907–919 76) Najafi, N., Mehri, S., Ghasemzadeh Rahbardar, M., Hosseinzadeh, H. Effects of alpha lipoic acid on metabolic syndrome: A comprehensive review. Phytotherapy Research, 2022, 36(6), 2300–2323 77) Mashayekhi-Sardoo, H., Mohammadpour, A.H., Mehri, S.,.Sahebkar, A., Imenshahidi, M.Diabetes mellitus aggravates ranolazine-induced ECG changes in rats. an international journal of arrhythmias and pacing 2022, 63(2), pp. 379–388. 78) Zanjani, N.R., Roohbakhsh, A., Moghimi, A., Mehri, S. Protective effect of Toll-like receptor 4 antagonist on inflammation, EEG, and memory changes following febrile seizure in Wistar rats. Behavioural Brain Research , 2022, 420, 113723 79) Ahmadi, A., Mortazavi, Z., Mehri, S., Hosseinzadeh, H. Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms. DARU, Journal of Pharmaceutical Sciencesthis. 2022, 30(2):351-366. 80) Khezri, A., Mohsenzadeh, M.S., Mirzayan, E..Mehri, S., Hosseinzadeh, H. Quetiapine attenuates the acquisition of morphine-induced conditioned place preference and reduces ERK phosphorylation in the hippocampus and cerebral cortex. American Journal of Drug and Alcohol Abuse , 2022, 48(4):422-432. 81) Ahmadi, A., Mortazavi, Z., Mehri, S., Hosseinzadeh, H. Scutellaria baicalensis and its constituents baicalin and baicalein as antidotes or protective agents against chemical toxicities: a comprehensive review. Naunyn-Schmiedeberg's Archives of Pharmacology, 2022, 395(11):1297-1329. 81) Heidari, S., Mehri, S., Hosseinzadeh, H.The genus Glycyrrhiza (Fabaceae family) and its active constituents as protective agents against natural or chemical toxicities. Phytotherapy Research, 2021, 35(12), 6552–6571 82) Salaramoli, S., Mehri, S., Yarmohammadi, F., Hashemy, SI., Hosseinzadeh, H. The effects of ginger and its constituents in the prevention of metabolic syndrome: A review. Iranian Journal of Basic Medical Sciences , 2022, 25 (6), 664-788. 83) Samakar, B., Mehri, S., Hosseinzadeh, H., A review of the effects of Urtica dioica (nettle) in metabolic syndrome. Iranian Journal of Basic Medical Sciences , 2022, 25 (5), 543-663. 84) Emadi, SA., Ghasemzadeh Rahbardar, M., Mehri, S., Hosseinzadeh, H. A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents. Iranian Journal of Basic Medical Sciences, 2022. 85) Barangi, S., Hosseini SM, Karimi G, Mehri, S. Fasudil attenuated 6-OHDA cytotoxicity in PC12 cells through inhibition of JAK/STAT and apoptosis pathways. Pharm Sci. 2022. doi:10.34172/PS.2022.33. 86) Mashayekhi-sardoo H, Kamali H, Mehri S, Sahebkar A, Imenshahidi M, Mohammadpour AH. Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats. Iranian Journal of Basic Medical Sciences , 2022;25(7):865-70. 87) Shayan, M., Mehri, SRazavi, B.M., Hosseinzadeh, H. Minocycline Protects PC12 Cells Against Cadmium-Induced Neurotoxicity by Modulating Apoptosis. Biological Trace Element Research. 2023, 201(4):1946-1954 88) Yarmohammadi, F., Barangi, S., Aghaee-Bakhtiari, S.H..Mehri, S., Karimi, G. Melatonin ameliorates arsenic-induced cardiotoxicity through the regulation of the Sirt1/Nrf2 pathway in rats. BioFactorsthis, 2023, 49(3), 620–635 89) Shayan, M., Mehri, S., Razavi, B.M., Hosseinzadeh, H. Minocycline Protects PC12 Cells Against Cadmium-Induced Neurotoxicity by Modulating Apoptosis. Biological Trace Element Research, 2023, 201(6), 2955–2962 90) Shayan, M., Barangi, S., Hosseinzadeh, H., Mehri, S. The protective effect of natural or chemical compounds against arsenic-induced neurotoxicity: Cellular and molecular mechanisms. Food and Chemical Toxicology., 2023, 175, 113691 91) Barangi, S., Ghodsi, P., Mehrabi, A., Hayes, A.W., Karimi, G. Melatonin attenuates cardiopulmonary toxicity induced by benzo(a)pyrene in mice focusing on apoptosis and autophagy pathways. Environmental Science and Pollution Research, 2023, 30(12), 33113–33123
Book
1) Karimi, G. Mehri, S. (2015). Current insights into mycotoxins (chapter). In Biological toxins and bioterrorism book. 2) Mehri, S. Razavi, BM. Hosseinzadeh, H. (2020). Safety and toxicity of saffron (chapter). In Saffron book.
Presentations 1) Hosseinzadeh, H., Shamsaie, F. and Mehri, S. Antioxidant Activity of Aqueous and Ethanolic Extracts of Crocus sativus L. Stigma and its Bioactive Constituents, Crocin and Safranl. International Symposium on Saffron a Herbal Medicine of 3rd Millennium, May 13 -14, 2009, Mashhad, Iran. Poster 2) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H. Acrylamide and Neurotoxicity. First Iranian Congress on Acrylamide and Its Challengess on Food Industry. May 27, 2010, Mashhad, Iran. Poster. 3) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H. Protective effect of crocin on acrylamide – induced cytotoxicity in PC 12 cells. 12 th Iranian Pharmaceutical Sciences Congress (IPSC 2010), August 2– 5, 2010, Zanjan, Iran. Poster 4) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H. Neurotoxicity of Acrylamide in occupational exposure. Iranian Congress of Addiction, Poisoning and nursing Care. October 27-29, 2010, Mashhad, Iran. Poster 5) Mehri, S. Shahsavand, Sh. Moallem, SA. Malaekeh, B. Moosavi, S.H. Nassirli,H. Safranal and Its Nanoliposoms- Induced Cytotoxicity in Hela and MCF7 cancer cell lines. The First International Student Congress on Cell and Molecular Medicine. February 17-19, 2011, Shiraz, Iran. Poster 6) Mehri, S. Hosseinzadeh, H. Mehdizadeh, R. Khooei, A. Parizadeh, M. Preventive effect if Crocus sativus L. stigma extract on biochemical, antioxidant and histopathological alterations in isoproterenol – induced cardiotoxicity in wistar rats. 12th Iranian Congress of Biochemistry & 4 th International Congress of Biochemistry & Molecular Biology, September 6-9, 2011. Mashhad, Iran. Oral 7) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H. Protective effect of crocin on Acrylamide- induced neurotoxicity in wistar rats. 20 th Iranian Congress of Physiology and pharmacology, 2011, Hamedan, Iran. Poster 8) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H. Apoptotic protein- expression profiles in rat cerebral cortex following exposure to acrylamide. 11 th International Iranian Toxicology Congress. September 13-15, 2011, Mashhad, Iran. Poster 9) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H. Crocin decreased acrylamide – induced neurotoxicity in wistar rat through oxidative stress and apoptosis pathway. 13 th Iranian Pharmaceutical Sciences Congress (IPSC 2012), Isfahan-Iran. Oral 10) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H, Khoei. Vitamin E as an antiapoptotic and antioxidant agent in Acrylamide-induced neurotoxicity in wistar rats. 12 th Iranian Toxicology Congress. May 15-17, 2013, Sari- Iran. Poster 11) Mehri, S., Illes, P., Reidel, T. P2X7 receptors at neurons and astrocytes of cultured hippocampal and cortical cells of the rat. 21st International Iranian Congress of Physiology and Pharmacology- 23-27 August, 2013, Tabriz-Iran. Oral Presentation. 12) Mehri, S. Meshki, MA., Hosseinzadeh, H. Evaluation of linalool effect on acrylamide induced neurotoxicity in wistar rat. 21st International Iranian Congress of Physiology and Pharmacology- 23-27 August, 2013, Tabriz-Iran. Poster Presentation. 13) Mehri, S. Hosseinzadeh, H., Abnous, Kh., Mousavi, S.H, Khoei. Reduction of acrylamide-induced neurotoxicity in cerebellum tissue following administration of crocin. 14) Mehri, S. Khezri, A., Hosseinzadeh, H. Effect of quetiapine on attenuation of morphine-induced conditioned place preference: Evaluation of CREB, p-CREB, ERK and p-ERK proteins level in rat hippocampus. 13th Iranian International Congress of Toxicology. May 12-14, 2015, URMIA. Poster Presentation. 15) Mehri, S. Sajjadi, SS., Hosseinzadeh, H. Effects of clavulanic acid on the acquisition and reinstatement of morphineinduced conditioned place preference in mice. 1st International and 22 nd Iranian Congress of Physiology and Pharmacology. September 7-11, 2015, Kashan. Poster Presentation. 16) Mehri, S. Dadesh, Q., Hosseinzadeh, H. Neuroprotective effect of silymarin against acrylamide-induced neurotoxicity in both in vitro and in vivo assessments. The First International Cingress of Complementary and Alternative Medicine. October 7-9, 2015, Mashhad. Poster Presentation. 17) Mehri, S. Foroutan far, A., Hosseinzadeh, H. Hepatoprotective effect of punicalagin against acrylamide-induced toxicity in Wistar rat. 14th Iranian Pharmaceutical Sciences Congress, 1st Symposium of Biopharmaceutics and Pharmacokinetics. December 21-24, 2015, Tehran. Poster Presentation. 18) Mehri, S. Hosseinzadeh, H. , Shabani, F Silakhori, S. Clavulanic acid as a neuroprotective agent against neurotoxins: Role of oxidative stress and apoptosis. 6 th Basic and Clinical Neuroscience congress. December 20-22, 2017, Tehran. Poster Presentation. 19) Mehri, S. Adabizadeh, M. Rajabpour Moghaddam, M. Abnous, Kh. Hosseinzadeh, H. The effects of crocin on spatial memory impairment induced by hyoscine: Role of NMDA, AMPA, ERK and CaMKII signaling in rat hippocampus. 23 rd Iranian and 2 nd International Congress of Physiology and Pharmacology. February 15-18, 2018, Chabahar. Poster Presentation. 20) Mehri, S. Hosseinzadeh, H. Silakhori, S. Adelkhah, S. Effect of clavulanic acid on memory dysfunction: In vitro and in vivo assays. 24 rd Iranian and 3 rd International Congress of Physiology and Pharmacology. October 30-November 1, 2019, Tehran. Poster Presentation. 21) Mehri, S. Hosseinzadeh, H. Cheraghi Farmad, H. Ghasemzadeh Rahbardar, M. Selenium as a protective agent against acrylamide-induced neurotoxicity and hepatotoxicity in rats. 15th iranian congress of toxicology. November 19-22, 2019, Tehran. Oral Presentation.
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