Curriculum Vitae
Bizhan Malaekeh-Nikouei (Pharm.D, Ph.D.)
Professor in Pharmaceutics, School of Pharmacy and Nanotechnology Research Center, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran P.O. Box: 91775-1365 Phone: +98 511 8823255-6 or +98 511 7112611 E-mail: این آدرس ایمیل توسط spambots حفاظت می شود. برای دیدن شما نیاز به جاوا اسکریپت دارید
Gender: male Date of birth: June 24th, 1976 Place of birth: Mashhad, Iran Residence: Mashhad, Iran Marital status: Married Number of Children: 2
Education: - Sabbatical (6 months) in University of Utah, USA (2013) - Research fellowship (6 months) in University of Queensland, Australia (2005) - Ph.D. in Pharmaceutics from School of Pharmacy, Mashhad University of Medical Sciences (2001-2006) - Pharm.D. from School of Pharmacy, Tabriz University of Medical Sciences (1994 -1999)
Research interests: Particulate drug delivery systems including Microspheres and Nanospheres, Liposomes, Solid lipid nanoparticles (lipospheres), Nanobiotechnology, Designing of non-viral vectors, Targeted drug delivery
Editorial Board Member:
Publications: - Hasanzadeh D., Malaekeh-Nikouei B., 1997, Quantitative analysis of H2-blockers by FT-IR: comparison with HPLC method, Pharmaceutical Sciences (Journal of Tabriz Faculty of Pharmacy), 3, 25-32. (Persian) - Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2004, Preparation and characterization of biodegradable microspheres encapsulated with cyclosporine A using different grades of PLGA, Iranian Journal of Basic Medical Sciences, 7, 4, 240-249 (Persian). - Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiee A., 2005, Preparation of fusogenic liposomes encapsulated with cyclosporine A and evaluation of its immunosuppressive effects on human T-cells, Pharmaceutical Sciences (Journal of Tabriz Faculty of Pharmacy), 2, 1-9 (Persian). - Jaafari M. R., Malaekeh-Nikouei B., Nasirli H., Hosseinzadeh H., 2005, Formulation of topical liposomes encapsulated with triamcinolone and comparison of their anti-inflammatory effects with available conventional topical ointment in mice, Iranian Journal of Basic Medical Sciences, 8, 3, 195-201 (English). - Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Davies N. M., 2005, Preparation and characterization of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Iranian Journal of Pharmaceutical Sciences, 1, 4, 195-201 (English). - Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2006, The effect of different grades of PLGA on characteristics of microspheres encapsulated with cyclosporine A, Current Drug Delivery, 3, 4, 343-349 (English). - Malaekeh-Nikouei B., 2006, Liposomes as novel drug delivery system, Razi, 211, 59-64 (Persian). - Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Davies N. M., 2006, The effect of complexation on characteristics and drug release of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Journal of Drug Delivery Science and Technology, 16(5), 345-350 (English). - Malaekeh-Nikouei B., Nassirli H., Davies N. M., 2007, Enhancement of cyclosporine aqueous solubility using α- and hydroxypropyl β-cyclodextrin mixtures, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 59 (3-4), 245-250 (English). - Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., 2007, Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A, Saudi Pharmaceutical Journal, 15, 3-4, 176-182 (English). - Malaekeh-Nikouei B., Abrishami M., Zarei S., 2008, Liposomal formulation of bevasizuamb for intravitreal administration: increased half-life, decreased side effects, Iranian Journal of Medical Hypotheses and Ideas, 2:4, (Persian). - Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2008, Preparation, characterization and mucoadhesive properties of chitosan coated microspheres encapsulated with cyclosporine A, Drug Development and Industrial Pharmacy, 34, 5, 492-498 (English). - Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiee A., 2008, The Enhancement of Immunosuppressive Effects of Cyclosporine A on Human T-Cells Using Fusogenic Liposomes, Colloids and Surfaces B:Biointerfaces, 67, 238-244 (English). - Abrishami M., Zarei-Ghanavati S., Soroush D., Rouhbakhsh M., Jaafari M. R., Malaekeh-Nikouei B., 2009, Preparation, characterization and in vivo evaluation of nanoliposomes encapsulated bevacizuamb for Intravitreal administration, Retina, 29, 5, 699-703 (English). - Malaekeh-Nikouei B., Davies N. M., 2009, Double loading of cyclosporine A in liposomes using cyclodextrin complexes, PDA Journal of Pharmaceutical Science and Technology, March-April, 63(2), 139-148 (English). - Ramezani M., Khoshhamdam M., Dehshahri A., Malaekeh-Nikouei B., 2009, The influence of size, lipid composition and bilayer Tm on the transfection efficiency of nanolipoplexes, Colloids and Surfaces B:Biointerfaces, 72(1), 1-5 (English). - Malaekeh-Nikouei B., Malaekeh-Nikouei , Kazemi Oskuee R., Ramezani M., 2009, Preparation, characterization and transfection efficiency of nanoliposomes modified with oligoamines as gene carrier, Nanomedicine: Nanotechnology, Biology, and Medicine, 5, 457–462 (English). - Malaekeh-Nikouei B., Sajadi Tabassi S.A., Ashari H., Gholamzadeh A., 2009, Evaluation the effect of cyclodextrin complexation on aqueous solubility of fluorometholone to achieve ophthalmic solution, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 65, 335-340 (English). - Ramezani M., Khakshoor T., Malaekeh-Nikouei M., Malaekeh-Nikouei B., 2010, The effect of linear PEI on characteristics and transfection efficiency of PEI-based cationic nanoliposomes, Iranian Journal of Basic Medical Sciences, 4,1, 82-88 (English). - Motaharinia J., Ramezani M., Malaekeh-Nikouei M., Malaekeh-Nikouei B., 2011, Liposome-linear polyethyleneimine-DNA Nanocomplexes for Gene Delivery: Preparation, Characterization and In Vitro Transfection Activity, Current Nanoscience, 7, 587-593 (English). - Mousavi S.H., Moallem S.A., Mehri S., Shahsavand S., Nassirli H., Malaekeh-Nikouei B., 2011, Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form, Pharmaceutical Biology, 49(10), 1039–1045, (English). - Malaekeh-Nikouei B., Banaee T., Aghamohammadian J., Mosallaei N., Mohajeri SA., 2011, Quantitative LC Analysis of Cyclosporine A in Ocular Samples, Chromatographia, 73:817–821, (English). - Malaekeh-Nikouei B., Golmohammadzadeh S., Hosseini M., Nassirli H., 2011, Preparation and characterization of liposomes encapsulated with clindamycin and tretinoin, Pharmacie Globale (IJCP), 6 (03), (English). - Asili J., Mosallaei N., Shaterzadeh A., Malaekeh-Nikouei B., 2012, Preparation and characterization of liposomes containing methanolic extract of aerial parts of Platycladus orientalis (L.) Franco, Avicenna Journal of Phytomedicine, 2, 1, 17-23 (English). - Ramezani M., Malaekeh-Nikouei B., Motaharinia J., Malaekeh-Nikouei M., 2011, Glactosylated liposome-polyethyleneimine-DNA nanocomplexes as a non-viral vector, Pharmacie Globale (IJCP), 10 (03) (English). - Tavallaie S., Zobeiri M., Haghighat-Khazaee Z., Hassanzadeh-Khayyat M., Nassirli H., Malaekeh-Nikouei B., Sahebkar A., Ghayour-Mobarhan M., 2012, Serum vitamin E concentration in Iranian population with angiography defined coronary artery disease, Asian Biomedicine, 6, 1, 19-25 (English). - Mohajeri SA, Malaekeh-Nikouei B., Sadegh H., 2012, Development of a pH-responsive drug delivery system for diclofenac using molecularly imprinted polymers, Drug Development and Industrial Pharmacy, 38(5):616-22 (English). - Malaekeh-Nikouei B., Sajadi Tabassi S.A., Gerayeli G., Arab Salmani M., Gholamzadeh A., 2012, The effect cyclodextrin mixtures on the aqueous solubility of beclomethasone dipropionate, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 72, 383-387 (English). - Rafiee E., Eavani S., Malaekeh-Nikouei B., 2012, 12-Tungstophosphoric Acid Immobilized on γ-Fe2O3@SiO2 Core–Shell Nanoparticles: An Effective Solid Acid Catalyst for the Synthesis of Indole Derivatives in Water, Chemistry Letters, 41, 4, 438-440 (English). - Malaekeh-Nikouei B., Abbasi Ghaeni F., Motamedshariaty , Mohajeri SA, 2012, Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses, Journal of Applied Polymer Science, 126, 1, 387-394 (English). - Mosallaei N., Banaee T., Farzadnia M., Abedini E, Ashraf H, Malaekeh-Nikouei B., 2012, Safety evaluation of nanoliposomes containing cyclosporine A after ocular administration, Current Eye Research, 37, 6, 453-456 (English). - Ramezani M., Malaekeh-Nikouei B., Malekzadeh S., Baghayeripour M.R., Malaekeh-Nikouei M., 2012, The effect of lipopolymer structure on the transfection efficiency of hydrophobic PEI-based cationic nanoliposomes, Current Nanoscience, 8, 5, 680-684 (English). - Zarei-Ghanavati S., Malaekeh-Nikouei B., Pourmazar R., Seyedi , 2012, Preparation, characterization and in vivo evaluation of microspherical triamcinolone acetonide after intravitreal administration, Journal of Ocular Pharmacology and Therapeutics, 28 (5), 502-506 (English). - Malaekeh-Nikouei B., Fazly Bazzaz B.S., Soheili V., Mohammadian K., 2013, Problems in ophthalmic drug delivery: evaluation of interaction between preservatives and cyclodextrins, Jundishapur Journal of Microbiology, 6(5), e6333 (English). - Hosseinzadeh H., Ramezani , Tavakoli Anaraki N., Malaekeh-Nikouei B., Mohammadpour A.H., 2013, Development and validation of extraction and HPLC method for determination of crocetin in human serum samples, Iranian Journal of Basic Medical Sciences, 15, 1, 47-55 (English). - Malaekeh-Nikouei B., Mousavi SH, Shahsavand S, Mehri S, Nassirli H, Moallem SA., 2013, Assessment of cytotoxic and apoptogenic properties of safranal and nanoliposomal safranal in various cancer cell lines, Phytotherapy Research, 27, 1868-1873 (English). - Malaekeh-Nikouei B., Golmohammadzadeh S., Salmani-Chamanabad S., Mosallaei N., Jamialahmadi K., 2013, Preparation, characterization and moisturizing effect of liposomes containing glucosamine and N-acetyl glucosamine, Journal of Cosmetic Dermatology, 12, 96-102 (English). - Malaekeh-Nikouei B., Vahabzadeh S.A., Mohajeri S.A., 2013, Preparation of a molecularly imprinted soft contact lens as a new ocular drug delivery system for dorzolamide, Current Drug Delivery, 2, 3, 279 -285 (English). - Mosallaei , Jaafari M.R., Hanafi-Bojd M.Y., Golmohammadzadeh S., Malaekeh-Nikouei B., 2013, Docetaxel loaded solid lipid nanoparticles: Preparation, characterization, in-vitro and in-vivo evaluations, Journal of Pharmaceutical Sciences, 102, 6, 1994-2004 (English). - Iranshahi M., Esfahanizadeh T., Jalili-Jamshidian E., Hanafi-Bojd M.Y., Malaekeh-Nikouei B., 2013, Improvement the aqueous solubility of the prenylated coumarins using cyclodextrin complexation, International Journal of Pharmaceutical Research, 5, 3, 40-42 (English). - Eslampour A., Malaekeh-Nikouei B., Abrishami M., Bayani R., 2013, Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy, Journal of Ocular Pharmacology and Therapeutics, 29(7), 670-673 (English). - Nikofal S., MohajeriA., Banaee T., Malaekeh-Nikouei B., 2013, Evaluation of cyclosporine A eye penetration after administration of liposomal or conventional forms in animal model, Nanomedicine Journal, 1, 1, 52-58 (English). - Oskuee R.K., Mohtashami E., Golami L., Malaekeh-Nikouei B., 2014, Cationic liposomes-polyallylamine-plasmid nanocomplexes for gene delivery, Journal of Experimental Nanoscience, 9, 10, 1026-1034 (English). - Malaekeh-Nikouei , 2014, A brief report on Iranian Journal of Basic Medical Sciences in 2013, Iranian Journal of Basic Medical Sciences, 17, 3, 149 (Editorial) (English). - Fazly Bazzaz B.S., Khameneh , Jalili-Behabadi M., Malaekeh-Nikouei B., Mohajeri S.A., 2014, Preparation, characterization and antimicrobial study of a hydrogel (soft contact lens) material impregnated with silver nanoparticles, Contact Lens & Anterior Eye, 37, 149-152 (English). - Ramezani A., Mehrdad Iranshahi M., Hanafi-Bojd, M.H., Malaekeh-Nikouei B., 2014, Preparation, characterization and cytotoxic effects of nanoliposomes containing umbelliprenin, International Journal of Pharmaceutical Research, 6, 2, 79-86 (English). - Mahmoudi A., Oskuee R.K., Ramezani M., Malaekeh-Nikouei B., 2014, Preparation and in-vitro transfection efficiency evaluation of modified cationic liposome-polyethyleneimine-plasmid nanocomplexes as a novel gene carrier, Current Drug Delivery, 11, 5, 636-642 (English). - Moghadas Sharif N., Fazly Bazzaz S., Khameneh Bagheri B., Malaekeh-Nikouei B., 2015, The effect of nanoliposomes containing vancomycin and rifampin on Staphylococcus epidermidis biofilm, Drug Development and Industrial Pharmacy, 41, 3, 445-450 (English). - Oskuee R.K., Dosti F., Gholami L., Malaekeh-Nikouei B., 2015, A simple approach for producing highly efficient DNA carriers with reduced toxicity based on modified polyallylamine, Materials Science and Engineering C, 49, 290-296 (English). - Hanafi-Bojd Y., Jaafari M.R., Ramezanian Xue M., Amin M., Shahtahmasbi N., Malaekeh-Nikouei B., 2015, Surface Functionalized Mesoporous Silica Nanoparticles as an effective carrier for Epirubicin delivery to cancer cells, European Journal of Pharmaceutics and Biopharmaceutics, 89, 248-258 (English). - Oskuee R.K., Zakeri V., Gholami L., Malaekeh-Nikouei B., 2015, Preparation, characterization and transfection efficiency of nanoparticles composed of bromoalkane modified polyallylamine, Nanomedicine Journal, 2, 2, 111-120 (English). - Malaekeh-Nikouei , Roohbakhsh A., 2015, Iranian Journal of Basic Medical Sciences: 2014 in profile, Iranian Journal of Basic Medical Sciences, 18, 1, 1 (Editorial) (English). - Naseripour , Abrishami M., Ahad Sedaghat A., Mojtaba Abrishami M., Rezaei Kanavi M, Mosallaei N., Ghasemi Falavarjani K., Pourmatin R., Safarian O., Malaekeh-Nikouei B., 2016, Preparation and in vivo evaluation of nanoliposomes containing melphalan after intravitreal injection, Journal of Pharmaceutical Investigation, 46, 572-582 (English). - Gholamzadeh A., Amini S., Mohammadpour A.H., Vahabzadeh M., Fazelifar A.F., Fazlinezhad A., Dehghani M., Moohebati M., Dastani M., Malaekeh-Nikouie B., Falsoleiman H., 2015, Erythropoietin reduces post-PCI arrhythmias in patients with ST-elevation myocardial infarction, Journal of Cardiovascular Pharmacology, 65(6):555-61 (English). - Sadeghnia H., Zoljalali N., Hanafi-Bojd M.Y., Nikoofal-Sahlabadi , Malaekeh-Nikouei B., 2015, Effect of mesoporous silica nanoparticles on cell viability and markers of oxidative stress, Toxicology Mechanisms and Methods, 25, 6, 433-439 (English). - Hanafi-Bojd Y., Jaafari M.R., Ramezanian N., Xue M., Amin M., Shahtahmasbi N., Malaekeh-Nikouei B., 2016, Co-delivery of epirubicin and siRNA using functionalized mesoporous silica nanoparticles enhances in vitro and in vivo drug efficacy, Current Drug Delivery, 13, 7, 1176-1182 (English). - Naji-Tabasi S., Razavi S.M.A., Mohebbi , Malaekeh-Nikouei B., 2016, New studies on basil (Ocimum bacilicum L.) seed gum: Part I- Fractionation, physicochemical and surface activity characterization, Food Hydrocolloids, 52, 350-358 (English). - Oskuee R.K., Mahmoudi A., Gholami L., Rahmatkhah A., Malaekeh-Nikouei B., 2016, Cationic liposomes modified with polyallylamine as a gene carrier: Preparation, characterization and transfection efficiency evaluation, Advanced Pharmaceutical Bulletin, 6(4), 515-520 (English). - Mosallaei N., Mahmoudi A., Ghandehari H., Venkata Kashyap Yellepeddi V.K., Jaafari M.R., Malaekeh-Nikouei B., 2016, Solid Lipid Nanoparticles containing 7-ethyl-10-hydroxycamptothecin (SN38): Preparation, characterization, in vitro, and in vivo evaluations, European Journal of Pharmaceutics and Biopharmaceutics, 140, 42-50 (English). - Abrishami M., Abrishami , Mahmoudi A., Mosallaei N., Vakili Ahrari Roodi M., Malaekeh-Nikouei B., 2016, Solid lipid nanoparticles improves the diclofenac availability in vitreous after intraocular Injection, Journal of Drug Delivery, Article ID 1368481, 1-5 (English). - Mahyari, Mahyari B., Emami S.A., Malaekeh-Nikouei B., Jahanbakhsh S.P., Mohammadpour A.H., Sahebkar A., 2016, Evaluation of the efficacy of a polyherbal mouthwash containing Zingiber officinale, Rosmarinus officinalis and Calendula officinalis extracts in patients with gingivitis: A randomized double-blind placebo-controlled trial. Complementary Therapies in Clinical Practice 22, 93-98 (English). - Roohbakhsh A., Malaekeh-Nikouei , 2016, Iranian Journal of Basic Medical Sciences 2015 at a glance, Iranian Journal of Basic Medical Sciences, 19, 1, 1 (Editorial) (English). - Rezaee M., Kazemi Oskuee R., Nassirli , Malaekeh-Nikouei B., 2016, Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems, Journal of Controlled Release, 236, 1-14 (English) (Review). - Hanafi-Bojd M.Y., Ansari L., Malaekeh-Nikouei , 2016, Co-delivery of anticancer drugs and siRNA by mesoporous silica nanoparticles, Therapeutic Delivery, 7, 9, 649-655 (English) (Review). - Moeinpour F., Mohseni-Shahri F.S., Malaekeh-Nikouei , Nassirli H., 2016, Investigation into the interaction of losartan with human serum albumin and glycated human serum albumin by spectroscopic and molecular dynamics simulation techniques: A comparison study, Chemico-Biological Interactions, 257, 4-13 (English). - Zarei baygi F., Farhadian N., Malaekeh-Nikouei , Maghsoud Z., 2016, Co-encapsulation of tamoxifen citrate and quercetin using 2HP-β-cyclodextrin: A response surface experimental design, RSC Advances, 6, 111517-111525 (English). - Mohseni-Shahri F.S., Moeinpour F., Malaekeh-Nikouei , Nassirli H., 2017, Combined multispectroscopic and molecular dynamics simulation investigation on the interaction between cyclosporine A and β-lactoglobulin, International Journal of Biological Macromolecules, 95, 1-7 (English). - Malaekeh-Nikouei , 2017, Ciprofloxacin-imprinted hydrogels for drug sustained release in aqueous media, Pharmaceutical Development and Technology, 22, 1, 122-129 (English). - Oskuee R.K., Ramezanpoor M., Gholami L., Malaekeh-Nikouei B., 2017, Cholesterol improves the transfection efficiency of polyallylamine as a non-viral gene delivery vectors, Brazilian Journal of Pharmaceutical Sciences, 53(3):e00140 (English). - Sabouri-Rad S., Oskuee R.K., Mahmoodi A., Gholami L., Malaekeh-Nikouei , 2017, The effect of cell penetrating peptides on transfection activity and cytotoxicity of polyallylamine, BioImpacts, 2017;7(3):139-145 (English). - Amanolahi F., Ali Mohammadi A., Oskuee R.K., Malaekeh-Nikouei , 2017, A simple, sensitive and rapid isocratic reversed- phase high-performance liquid chromatography (HPLC) assay method for determination and stability study of curcumin in pharmaceutical samples, Avicenna Journal of Phytomedicine, 7, 5, 444-453 (English). - Hanafi-Bojd M.Y., Ansari L., Mosaffa F., Malaekeh-Nikouei , 2017, drug-resistant cancer cells, Nanomedicine Journal, 4(3), 135-141 (English). - Hanafi-Bojd M.Y., Moosavian Kalat S.A., Taghdisi S.M., Ansari L., Abnous K., Malaekeh-Nikouei , 2018, MUC1 Aptamer-conjugated mesoporous silica nanoparticles effectively target breast cancer cells, Drug Development and Industrial Pharmacy, 44, 1, 13-18 (English). - Malaekeh-Nikouei , Behzad M., Rezaei M., Golami L., Kazemi Oskuee R., 2017, Dexamethasone conjugated polyallylamine: synthesis, characterization, and in vitro transfection and cytotoxicity, Journal of Drug Delivery Science and Technology, 40, 172-179 (English). - Daneshmand S., Golmohammadzadeh S., Jaafari M.R., Movaffagh , Sahebkar A., Malaekeh-Nikouei B., 2018, Encapsulation challenges, the substantial issue in solid lipid nanoparticles characterization, Journal of Cellular Biochemistry, 119(6):4251-4264 (English) (Review). - Shahgholian N, Rajabzadeh G, Malaekeh-Nikouei B., 2017, Preparation and evaluation of BSA-based hydrosol nanoparticles cross-linked with genipin for oral administration of poorly water-soluble curcumin, International Journal of Biological Macromolecules, 104 (Pt A):788-798 (English). - Zarei H., Kazemi Oskuee R., Hanafi-Bojd M.Y., Gholami L., Ansari L., Malaekeh-Nikouei B., 2019, Enhanced gene delivery by polyethyleneimine coated mesoporous silica nanoparticles, Pharmaceutical Development and Technology, 24:1, 127-132 (English). - Ansari L., Jaafari M.R., Rohani Bastami , Malaekeh-Nikouei B., 2018, Improved anticancer efficacy of epirubicin by magnetic mesoporous silica nanoparticles: in vitro and in vivo studies, Artificial Cells, Nanomedicine, and Biotechnology, 46:2, 594-606 (English). - Mirhadi E., Rezaee , Malaekeh-Nikouei B., 2018, Nanotechnology-based products of berberine, a natural alkaloid of Berberis: Current status and perspectives, Biomedicine & Pharmacotherapy, 104, 465-473 (English). - Daneshmand S., Jaafari M.R., Movaffagh J., Malaekeh-Nikouei B., Iranshahi M., Moghaddam A.S., Najaran Z.T., Golmohammadzadeh S., 2018, Preparation, characterization, and optimization of auraptene-loaded solid lipid nanoparticles as a natural anti-inflammatory agent: In vivo and in vitro evaluations, Colloids and Surfaces B: Biointerfaces 164, 332–339 (English). - Ebrahimi Nik M., Momtazi A. A., Zamani P., Gholizadeh Navashenaq J., Iranshahi M., Jaafari M. R., Malaekeh-Nikouei B.,, 2019, Targeted-nanoliposomal Combretastatin A4 (CA-4) as an efficient anti-vascular candidate in the metastatic cancer treatment, Journal of Cellular Physiology, 234:14721-14733 (English). - Malaekeh-Nikouei B., Salarbashi D., 2018, Nanoencapsulation and delivery of curcumin using some carbohydrate based systems: A review, Nanomedicine Journal, 5(2): 57-61. - Faraji H., Nedaeinia R., Nourmohammadi E., Malaekeh-Nikouei B., Sadeghnia H.R., Ziapour S.P., Khoshdel Sarkarizi H., Kazemi Oskuee R., A Review on Application of Novel Solid Nanostructures in Drug Delivery, Journal of Nano Research, Vol. 53, 22-36 (English) (Review). - Malaekeh-Nikouei B., Rezaee M., Gholami L., Sanjar Mousavi N., Kazemi Oskuee R., 2018, Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery, Pharmaceutical Biology, 56:1, 519-527 (English). - Amanolahi F., Mohammadi A., Kazemi Oskuee R., Gholami L., Malaekeh-Nikouei B., 2018, Curcumin improved liposomal mitomycin-induced cell toxicity in bladder cancer cell, Nanomedicine Journal, 5(4): 235-244 (English). - Mirhadi , Malaekeh-Nikouei B., 2020, An updated review on therapeutic effects of nanoparticle-based formulations of saffron components (safranal, crocin, and crocetin), Journal of Pharmaceutical Investigation, 50:47–58 (English). - Mahmoudi A., Jaafari M.R., Ramezanian N., Gholami L., Malaekeh-Nikouei B., 2019, BR2 and CyLoP1 enhance In-vivo SN38 delivery using pegylated PAMAM dendrimers, International Journal of Pharmaceutics, 564, 77-89 (English). - Akbarzadeh M., Kazemi Oskuee R, Gholami L., Mahmoudi A., Malaekeh-Nikouei B., 2019, BR2 cell penetrating peptide improved the transfection efficiency of modified polyethyleneimine, Journal of Drug Delivery Science and Technology, 53, 101154 (English). - Alinejad-Mofrad E., Malaekeh-Nikouei B., Gholami L., Mousavi S.H., Sadeghnia H.R., Mohajeri M., Darroudi M., Oskuee R.K., 2019, Evaluation and comparison of cytotoxicity, genotoxicity, and apoptotic effects of poly-L-lysine/plasmid DNA micro and nanoparticles, Human and Experimental Toxicology, 38(8), 983–991 (English). - Malaekeh-Nikouei B., 2020, Impacts of different organic amendments on soil degradation and phytotoxicity of metribuzin, International Journal of Recycling of Organic Waste in Agriculture. - Arabi L., Malaekeh-Nikouei B., Roohbakhsh A., Fazly Bazzaz B.S., 2020, Iranian Journal of Basic Medical Sciences: 2019 in retrospect, Iranian Journal of Basic Medical Sciences, 23, 1, 1-2. - Nassirizadeh S., Malaekeh-Nikouei B., 2020, Solid lipid nanoparticles and nanostructured lipid carriers in oral cancer drug delivery, Journal of Drug Delivery Science and Technology, 55, 101458 (English). - Bazrgari F., Khameneh B., Fazly Bazzaz B.S., Mahmoudi A., Malaekeh-Nikouei B., 2020, Effect of the nanoliposomal formulations of rifampin and n-acetyl cysteine on Staphylococcus epidermidis biofilm, Nanomedicine Journal, 7, 2, 131-137 (English). - Charmforoushan A., Rezaee Roknabadi M., Shahtahmassebi N., Malaekeh-Nikouei B.,, 2020, Low temperature facile synthesis of pseudowollastonite nanoparticles by the surfactant-assisted sol-gel method, Materials Chemistry and Physics, 243, 122629 (English). - Abrishami M., Motamed Shariati M., Malaekeh-Nikouei B., Sadat Tajani A., Mahmoudi A., Abrishami M., Khameneh B., 2020, Preparation and in vivo evaluation of nanoliposomes containing vancomycin after intravitreal injection in albino rabbits. Iranian Journal Basic Medical Sciences 23, 551-555. - Ansari L., Derakhshi M., Bagheri E., Shahtahmassebi N., Malaekeh-Nikouei B., 2020, Folate conjugation improved uptake and targeting of porous hydroxyapatite nanoparticles containing epirubicin to cancer cells, Pharmaceutical Development and Technology, 25, 5, 601-609 (English).
xSaman Mahyari Search for articles by this author Affiliations
Amirhossein Sahebkar Search for articles by this author Affiliations- Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran - Metabolic Research Centre, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia آرام بستان، محبت محبي، محمدحسين حداد خداپرست، مهدي وريدي، بيژن ملائكه نيكوئي، بررسي ساختار اسيد چرب و خصوصيات فيزيكوشيميايي روغن دانه مرو (Salvia macrosiphon، Boiss)، فصلنامه پژوهشهاي علوم و صنايع غذايي ايران، سال نهم، شماره 3 (پاییز 1392)، صفحه 279-283. نرگس شاهقلیان، قدیر رجب زاده، بیژن ملائکه نیکوئی، بررسی نانوکمپلکس آلبومین سرم گاوی-کورکومین به روش طیف سنجی فلوئورتابی، نشریه پژوهش های کاربردی در شیمی، سال نهم، شماره 4، زمستان 94، 5-11. فرزانه حاجی احمدی، اکبر درخشان، ملیحه نیک اندیش، بیژن ملائکه نیکوئی، تهیه قطره چشمی تاکرولیموس با استفاده از سیکلودکسترین ها، مجله دانشگاه علوم پزشکی بیرجند، 1396، 24(1)، 19-27. علی دینی، ناصر صداقت، سید محمدعلی رضوي ،آرش کوچکی، بیژن ملائکه نیکویی، تأثیر دما و سرعت جریان هوا بر سینتیک خشک شدن حین فرآیند برشته کردن پسته با جریان هواي داغ، نشریه ماشینهاي کشاورزي،1396، جلد7، شماره 2، 401-414.
Presentations:
- Malaekeh-Nikouei B., Ansari L., Jaafari M.R., Rohani Bastami T., Synthesis, characterization and in vivo evaluation of epirubicin loaded magnetic mesoporous silica nanoparticles, 23rd Dubai International Pharmaceutical & Technology Conference & Exhibition, 27 Feb-1 Mar 2018, Dubai, UAE. - Malaekeh-Nikouei B., Mosallaei N., Mahmoudi A., Ghandehari H., Venkata Kashyap Yellepeddi V.K., Jaafari M.R., Solid Lipid Nanoparticles containing 7-ethyl-10-hydroxycamptothecin (SN38): Preparation, characterization, in vitro, and in vivo evaluations, 7th Iranian Controlled Release Conference, 21-23 February 2017, Kerman, Iran. - Malaekeh-Nikouei B., Oskuee R.K., Ramezanpour M., Gholami L., Cholesterol improves the transfection efficiency of polyallylamine as a non-viral gene delivery vectors, MipTec2016, 19-23 September 2016, Basel, Switzerland - Malaekeh-Nikouei B., Nanomedicine, The 6th Annual Meeting of The Iranian Research Association for Vision and Ophthalmology, March 3-4, 2016, Tehran, Iran (Invited Speaker). - Malaekeh-Nikouei B., Abrishami , Abrishami M., Mahmoudi A., Mosallaei N., Vikili Ahrari Roodi M., Preparation, Characterization, and In Vivo Evaluation of Solid Lipid Nanoparticles Containing Diclofenac after Intravitreal Administration, 1st International Gazi Pharma Symposium, November 12–15, 2015, Antalya, Turkey. - Malaekeh Nikouei B., Oskuee R.K., Doosti F., Preparation, characterization and transfection efficiency of nanoparticles composed of modified polyallylamine, MipTec2014, 23-25 September 2014, Basel, Switzerland. - Malaekeh-Nikouei B., Banaee T., Mosallaei N., Farzadnia M., Abedini E., Ashraf H., Preparation, characterization and safety evaluation of nanoliposomal formulations containing cyclosporine A, NanoFormulation, 28 May-1 June 2012, Spain. - Malaekeh-Nikouei B., Ramezani M., Arabi L., Transfection efficiency of hydrophobic polyethyleneimine-based cationic nanoliposomes, Nanoscience and Nanotechnology Conference, September 19-23, 2011, Italy. - Malaekeh-Nikouei B., Zarei-Ghanavati S., Pourmazar R., Seyedi S., Microspheres containing triamcinolone acetonide for intravitreal administration: preparation, characterization and in vivo evaluation, 5th Iranian Controlled Release Conference, October 4-6, 2011, Mashhad, Iran. - Malaekeh-Nikouei B., Ramezani M., and Malaekeh-Nikouei M., Galactosylated liposmes-polyethyleneimine-DNA Nanocomplexes for gene delivery, Nano Thailand 2010, November 18-20, 2010, Thailand. - Malaekeh-Nikouei B., Ramezani M., Motaharinia J., and Malaekeh-Nikouei M., The Cationic liposome-polyethyleneimine-DNA complexes for gene delivery: Preparation, characterization, and transfection in vitro, 12th Iranian Pharmaceutical Sciences Conference, August 2-5, 2010, Zanjan, Iran. - Malaekeh-Nikouei B., Ramezani M., and Malaekeh-Nikouei M., Preparation, Characterization and Transfection Efficiency of Galactosylated Nanolipoplexes as a Gene Carrier, 2010 Singapore Symposium on Drug Delivery Systems, January 20-24, 2010, Singapore. - Malaekeh-Nikouei B., Abrishami , Zarei-ghanavati S., Soroush D., Majid Rouhbakhsh M., Jaafari M. R., Preparation, characterization and in vivo evaluation of nanoliposomes encapsulated bevacizuamb (Avastin) for intravitreal administration, The Specialized Congress of Nanomedicine, Nanobiotechnology, Nanobiosensors and Nanomaterials, July 14-16, 2009 , Mashhad, Iran. - Malaekeh-Nikouei B., Ramezani M., Nazari S., Khakshour T., Preparation, characterization and transfection efficiency of nanoliposmes modified with lipopolymers constructed from polyethyleneimine and acrylate derivatives, 4th Iranian Controlled Release Conference, October 6-8, 2009, Zanjan, Iran - Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Afshin Samiei, The effect of phospholipid type and size on immunosuppressive activities of liposomes encapsulated with cyclosporine A, 11th Liposome Research Days Conference, July 2008, Yokohama, Japan. - Malaekeh-Nikouei B., Ramezani M., Malaekeh-Nikouei M., Kazemi Oskuee R., Preparation, characterization and transfection efficiency of nanoliposomes modified with oligoamines as gene carrier, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran. - Gholamzadeh A., Ashari H., Malaekeh-Nikouei B., Sajadi Tabassi S.A., Evaluation of sulphobutylether β-cyclodextrin and hydroxypropyl γ-cyclodextrin complexation on aqueous solubility of fluorometholone, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran. - Shahsavand S., Mehri S., Moallem S.A., Mosavi S.H., Malaekeh-Nikouei B., Assessment of cytotoxic and apoptogenic properties of crocin and its nanoliposomes in various cancer cell lines, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran. - Mehri S., Shahsavand S., Moallem S.A., Mosavi S.H., Malaekeh-Nikouei B., Assessment of cytotoxic and apoptogenic properties of safranal and its nanoliposomes in various cancer cell lines, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran. - Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A, The Third Iranian Conference of Novel Drug Delivery Systems, June 2007, Tehran, Iran. - Sajadi S. A., Malaekeh-Nikouei B., Jaafari M. R., Davies N. M., The effect of complexation on characteristics of and drug release from PLGA microspheres loaded by cyclosporine-cyclodextrin complex, 33rd Annual Meeting and Exposition of the Controlled Release Society, July 2006, Vienna, Austria. - Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Preparation and characterization of chitosan coated microspheres encapsulated with cyclosporine A, 10th Iranian Pharmaceutical Sciences Conference, Aug 2006, Tehran, Iran. - Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiei , The enhancement of immunosuppressive effects of cyclosporine A on human T-cells using fusogenic liposomes, 10th Iranian Pharmaceutical Sciences Conference, Aug 2006, Tehran, Iran. - Sajadi S. A., Malaekeh-Nikouei B., Jaafari M. R., Preparation and characterization of biodegradable microspheres encapsulated with Cyclosporine A using different grades of PLGA, 1ST Pharmaceutical Sciences Fair & Exhibition, June 2005, Nice, France. - Malaekeh-Nikouei B., et al., Formulation of topical liposomes encapsulated with triamcinolone and comparison of their anti-inflammatory effects with available conventional topical ointment in mice, 9th Seminar of Pharmaceutical Sciences, Aug 2004, Tabriz, Iran. - Malaekeh-Nikouei B., et al., Preparation and characterization of biodegradable microsphere encapsulated with Cyclosporine A using different grades of PLGA, 9th Seminar of Pharmaceutical Sciences, Aug 2004, Tabriz, Iran. - Malaekeh-Nikouei B., et al., Comparison of different physicochemical analysis methods of H2-blockers, 1st Seminar of Pharmaceutical Methodology, Sep 2001, Mashhad, Iran. - Hasanzadeh D., Malaekeh-Nikouei B., Development of quantitative FT-IR analysis of H2-blockers: comparison with the HPLC methodology, Proc. 3rd World Meeting APV/APGI, April 2000, Berlin, Germany.
Book: - Stuart S., Modern Infrared Spectroscopy, 2002, Tabriz University of Medical Sciences (Translation to Persian). - Malaekeh-Nikouei B., Hanafi-Bojd M.Y., Aghebati T., Mosallaei N., 2011, Nanoparticulate drug delivery systems, Mashhad University of Medical Sciences, (Writing in Persian).
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