فعالیتهای تحقیقاتی دکتر جمال شمس آرا

امتیاز کاربران

ستاره فعالستاره فعالستاره فعالستاره فعالستاره فعال
 
  1. CV

    Jamal Shamsara

    Associate professor

    Pharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Pharm.D.,  Ph.D

    E-mail address: shamsaraj[at]mums.ac.ir, j_shamsara[at]yahoo.com

     

    Google Scholar profile:   https://scholar.google.com/citations?user=VX32ZGEAAAAJ&hl=en

     

    PubMed:       http://www.ncbi.nlm.nih.gov/pubmed/?term=Jamal+Shamsara

     

    Education

     2000-2006   Pharmacy                                               Pharm. D.      MUMS

     2006-2011    Pharmaceutical Biotechnology             Ph.D.             MUMS

     

    Research interests

    Virtual screening (structure based and ligand based), QSAR studies, Structural bioinformatics, Molecular medicine

     

    Teaching

    Advanced practical medicinal chemistry

     

    Pharmacy training course

    Computational drug design (workshop)

    Homology Modeling (workshop)

     

    Papers

    1- Ramezani, M and Shamsara, J. Application of DPD in the design of polymeric nano-micelles as drug carriers. Journal of Molecular Graphics and Modelling. In press.

    2-Shamsara, J. CDocker: a tool for performing cross-docking using Autodock Vina. Springerplus. In press.

    3-Shamsara, J and Shahir-Sadr A. Developing a CoMSIA model for inhibition of COX-2 by resveratrol derivatives. Iranian journal of Pharmaceutical Research. In press.

    4-Ramezani, M and Shamsara, J. A Cross-Docking Study on Matrix Metalloproteinase Family. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. (2016) 14, 1-8

    5-Shamsara, J. Considering rotatability of hydroxyl groups for the active site residues of MMP-13 in retrospective virtual screening campaigns. The Open Medicinal Chemistry Journal. (2016), 10: 1-6.

    6-Gholami, O and Shamsara, J. Comparison of the cytotoxic effects of umbelliprenin and auraptene. International Journal of Pharmacy and Pharmaceutical Sciences. (2015) 8 (1).

    7-Hadizadeh F., Shamsara J. Receptor-based 3D-QSAR approach to find selectivity features of flexible similar binding sites: case study on MMP-12/MMP-13. International Journal of Bioinformatics Research and Applications (2015) 11 (4): 326-346.

    8-Shamsara J. Evaluation of 11 Scoring Functions Performance on Matrix Metalloproteinases. International Journal of Medicinal Chemistry (2014) 2014.

    9-Shamsara J and Shahir-Sadr A. A Predictive HQSAR Model for a Series of Tricycle Core Containing MMP-12 Inhibitors with Dibenzofuran Ring. International Journal of Medicinal Chemistry (2014) 2014.

    10-Shamsara J. A study on druggability of MIA as a promising approach for inhibition of metastasis. International Journal of Computational Biology and Drug Design (2014) 7: 80-95.

    11-Mohammadpour AH, Nazemian F, Khaiat MH, Tafaghodi M, Salari P, Charkazi S, Naghibi M and Shamsara J. Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2014) 25: 73-78.

    12-Mohammadpour AH, Falsoleiman H, Shamsara J, Abadi GA, Rasooli R and Ramezani M. Pentoxifylline decreases serum level of adhesion molecules in atherosclerosis patients. Iranian Biomedical Journal (2014) 18: 23-27.

    13-Mohammadpour AH, Nazemian F, Shamsara J, Baf M, Ghorbani M and Moallem SA. Effects of omega-3 administration on concentration of serum inflammatory makers in renal transplant recipient. African Journal of Pharmacy and Pharmacology (2013) 7: 2021-2024.

    14-Mohammadpour AH, Moallem SA, Bafandegan M, Shamsara J and Nazemian F. Effects of omega-3 administration on homocysteine serum concentration in renal transplant recipient. Journal of Pharmaceutical Care (2013) 1: 25-28.

    15-Shamsara J, Mohammadpour AH, Behravan J, Falsoleiman H and Ramezani M. Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients. Immunopharmacology and Immunotoxicology (2012) 34: 523-529.

    16-Shamsara J, Behravan J, Falsoleiman H, Mohammadpour AH and Ramezani M. The effects of pentoxifylline administration on NFKB P50 transcription factor expression. ARYA Atherosclerosis (2012) 7: 133-137.

    17-Mohammadpour AH, Shamsara J, Nazemi S, Ghadirzadeh S, Shahsavand S and Ramezani M. Evaluation of RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification: a pilot study. Thrombosis (2012) 2012.

    18-Mohammadpour AH, Nazemi S, Foroughi M, Ghorbani M, Shamsara J and Behravan J. Evaluation of the association between AT 1R1166C polymorphism and the incidence of cad and CAC score in the Iranian population. Archives of Biological Sciences (2012) 64: 401-408.

    19-Moallem SA, Hadizadeh F, Abadi FA, Shahraki M and Shamsara J. Synthesis and evaluation of pyridinyltriazoles as inhibitors of p38 MAP kinase. Iranian Journal of Basic Medical Sciences (2012) 15: 945-950.

    20-Shamsara J, Behravan J, Falsoleiman H, Mohammadpour AH, Rendeirs J and Ramezani M. Pentoxifylline administration changes protein expression profile of coronary artery disease patients. Gene (2011) 487: 107-111.

    21-Ramezani M, Nazemian F, Shamsara J, Koohrokhi R and Mohammadpour AH. Effect of Omega-3 Fatty Acids on Plasma Level of 8-Isoprostane in Kidney Transplant Patients. Journal of Renal Nutrition (2011) 21: 196-199.

    22-Mohammadpour N, Elyasi S, Vahdati N, Mohammadpour AH and Shamsara J. A review on therapeutic drug monitoring of immunosuppressant drugs. Iranian Journal of Basic Medical Sciences (2011) 14: 485-498.

    23-Mohammadpour AH, Nazemian F, Moallem SA, Alamdaran SA, Asad-Abadi E and Shamsara J. Correlation between heat-shock protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients. Iranian Journal of Kidney Diseases (2011) 5: 260-266.

    24-Mohammadpour AH, Foroughipour M, Azarpazhooh MR, Khayat MH, Rezaee S, Aghebati T and Shamsara J. Comparison of valproic acid clearance between epileptic patients and patients with acute mania. Iranian Journal of Basic Medical Sciences (2011) 14: 546-550.

    25-Moallem SA, Nazemian F, Eliasi S, Alamdaran SA, Shamsara J and Mohammadpour AH. Correlation between cathepsin D serum concentration and carotid intima-media thickness in hemodialysis patients. International Urology and Nephrology (2011) 43: 841-848.

    26-Lotfi M, Afsharnezhad S, Raziee HR, Ghaffarzadegan K, Sharif S, Shamsara J, Lary S and Behravan J. Immunohistochemical assessment of MGMT expression and p53 mutation in glioblastoma multiforme. Tumori (2011) 97: 104-108.

    27-Nazemian F, Karimi G, Moatamedi M, Charkazi S, Shamsara J and Mohammadpour AH. Effect of silymarin administration on TNF-α serum concentration in peritoneal dialysis patients. Phytotherapy Research (2010) 24: 1654-1657.

    28-Mohammadpour A, Ramezani M, Nazemi S, Falsoleiman H, Shamsara J and Ghadirzadeh S. RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification. in EUROPEAN HEART JOURNAL. 2010. OXFORD UNIV PRESS GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND.

    29-Shamsara J, Sharif S, Afsharnezhad S, Lotfi M, Raziee HR, Ghaffarzadegan K, Moradi A, Rahighi S and Behravan J. Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma. Cancer Investigation (2009) 27: 825-829.

    30-Shamsara J, Ramezani M and Mohammadpour AH. The RANKL: Osteoprotegerin (OPG) ratio as a new biomarker for coronary artery disease. Iranian Journal of Medical Hypotheses and Ideas (2009) 3.

    31-Shamsara J, Ramezani M and Mohammadpour AH. Curcumin as a novel plaque stabilizing agent in prevention of acute coronary syndrome. Iranian Journal of Medical Hypotheses and Ideas (2009) 3.

    32-Shamsara J, Ramezani M and Mohammadpoor AH. Why homocysteine-lowering therapy does not have beneficial effects on patients with cardiovascular disease? Bioscience Hypotheses (2009) 2: 13-15.

    33-Roohbakhsh A, Shamsara J, Khayyat MH and Karimi G. Inhibition of xanthine oxidase by some Iranian plant remedies used for gout. Pharmacologyonline (2009) 3: 1031-1036.

    34-Foroughipour M, Mohammadpour AH, Vahdati Mashhadian N, Hasanzadeh KM, Azarpazhouh MR, Mokhber N, Aghebati T and Shamsara J. Therapeutic drug monitoring of valproic acid in patients with monotherapy at steady state. Iranian Journal of Basic Medical Sciences (2009).

    35-Hosseinzadeh H, Jaafari MR and Shamsara J. Selective inhibitory effect of adenosine A1 receptor agonists on the proliferation of human tumor cell lines. Iran Biomed J (2008) 12: 203-8.